Show simple item record

dc.contributor.authorWhite, Gavin R M
dc.contributor.authorKelsey, Anna M
dc.contributor.authorVarley, Jennifer
dc.contributor.authorBirch, Jillian M
dc.date.accessioned2009-10-12T12:27:24Z
dc.date.available2009-10-12T12:27:24Z
dc.date.issued2002-06-17
dc.identifier.citationSomatic glypican 3 (GPC3) mutations in Wilms' tumour. 2002, 86 (12):1920-2 Br. J. Canceren
dc.identifier.issn0007-0920
dc.identifier.pmid12085187
dc.identifier.doi10.1038/sj.bjc.6600417
dc.identifier.urihttp://hdl.handle.net/10541/84061
dc.description.abstractTumour and normal tissue from 41 male cases of Wilms' tumour were screened to determine the presence of sequence variants in the glypican 3 (GPC3) gene. Two non-conservative single base changes were present in tumour tissue only. These findings imply a possible role for GPC3 in Wilms' tumour development.
dc.language.isoenen
dc.subjectKidney Canceren
dc.subjectRenal Canceren
dc.subjectWilms Tumouren
dc.subject.meshDNA Primers
dc.subject.meshGlypicans
dc.subject.meshHeparan Sulfate Proteoglycans
dc.subject.meshHumans
dc.subject.meshKidney Neoplasms
dc.subject.meshMale
dc.subject.meshMutation
dc.subject.meshPolymerase Chain Reaction
dc.subject.meshPolymorphism, Single-Stranded Conformational
dc.subject.meshWilms Tumor
dc.titleSomatic glypican 3 (GPC3) mutations in Wilms' tumour.en
dc.typeArticleen
dc.contributor.departmentCancer Research UK Cancer Genetics Group, Paterson Institute for Cancer Research, Wilmslow Road, Manchester M20 4BX, UK.en
dc.identifier.journalBritish Journal of Canceren
html.description.abstractTumour and normal tissue from 41 male cases of Wilms' tumour were screened to determine the presence of sequence variants in the glypican 3 (GPC3) gene. Two non-conservative single base changes were present in tumour tissue only. These findings imply a possible role for GPC3 in Wilms' tumour development.


This item appears in the following Collection(s)

Show simple item record