AffiliationCancer Research UK Cancer Genetics Group, Paterson Institute for Cancer Research, Wilmslow Road, Manchester M20 4BX, UK.
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AbstractTumour and normal tissue from 41 male cases of Wilms' tumour were screened to determine the presence of sequence variants in the glypican 3 (GPC3) gene. Two non-conservative single base changes were present in tumour tissue only. These findings imply a possible role for GPC3 in Wilms' tumour development.
CitationSomatic glypican 3 (GPC3) mutations in Wilms' tumour. 2002, 86 (12):1920-2 Br. J. Cancer
JournalBritish Journal of Cancer