Somatic glypican 3 (GPC3) mutations in Wilms' tumour.

Authors
White, Gavin R M
Kelsey, Anna M
Varley, Jennifer
Birch, Jillian M
Affiliation
Cancer Research UK Cancer Genetics Group, Paterson Institute for Cancer Research, Wilmslow Road, Manchester M20 4BX, UK.
Issue Date
2002-06-17

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Abstract
Tumour and normal tissue from 41 male cases of Wilms' tumour were screened to determine the presence of sequence variants in the glypican 3 (GPC3) gene. Two non-conservative single base changes were present in tumour tissue only. These findings imply a possible role for GPC3 in Wilms' tumour development.
Citation
Somatic glypican 3 (GPC3) mutations in Wilms' tumour. 2002, 86 (12):1920-2 Br. J. Cancer
Journal
British Journal of Cancer
URI
http://hdl.handle.net/10541/84061
DOI
10.1038/sj.bjc.6600417
PubMed ID
12085187
Type
Article
Language
en
ISSN
0007-0920
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