Monotypic angiomyolipoma of the nasal cavity: a heretofore undescribed occurrence.
Affiliation
Department of Histopathology, Christie Hospital NHS Trust, Manchester, UK.Issue Date
2001-10
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A monotypic angiomyolipoma of the nasal cavity in a 34-year-old woman is described. Tumor cells were spindled or epithelioid and contained glycogen and diastase-resistant PAS-positive granules. There were few mitoses, and necrosis was absent, indicating a benign tumor. The stroma was markedly vascular, and a few adipocytes were seen in one area. Cells were positive for melanocyte and muscle markers. Electron microscopy revealed abundant dense granules. Although melanin was absent histochemically, it was present using a chemical assay, and the granules may, therefore, be atypical melanosomes. Fine actin filaments, attachment plaques and lamina were present. Initial assessment of the lesion indicated malignant melanoma, but the immunostaining and histologic features indicated monotypic angiomyolipoma. To the best of our knowledge, this is the first such case in the nasal cavity.Citation
Monotypic angiomyolipoma of the nasal cavity: a heretofore undescribed occurrence. 2001, 9 (4):309-15 Int. J. Surg. Pathol.Journal
International Journal of Surgical PathologyDOI
10.1177/106689690100900410PubMed ID
12574849Type
ArticleLanguage
enISSN
1066-8969ae974a485f413a2113503eed53cd6c53
10.1177/106689690100900410
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