Monotypic angiomyolipoma of the nasal cavity: a heretofore undescribed occurrence.
AffiliationDepartment of Histopathology, Christie Hospital NHS Trust, Manchester, UK.
MetadataShow full item record
AbstractA monotypic angiomyolipoma of the nasal cavity in a 34-year-old woman is described. Tumor cells were spindled or epithelioid and contained glycogen and diastase-resistant PAS-positive granules. There were few mitoses, and necrosis was absent, indicating a benign tumor. The stroma was markedly vascular, and a few adipocytes were seen in one area. Cells were positive for melanocyte and muscle markers. Electron microscopy revealed abundant dense granules. Although melanin was absent histochemically, it was present using a chemical assay, and the granules may, therefore, be atypical melanosomes. Fine actin filaments, attachment plaques and lamina were present. Initial assessment of the lesion indicated malignant melanoma, but the immunostaining and histologic features indicated monotypic angiomyolipoma. To the best of our knowledge, this is the first such case in the nasal cavity.
CitationMonotypic angiomyolipoma of the nasal cavity: a heretofore undescribed occurrence. 2001, 9 (4):309-15 Int. J. Surg. Pathol.
JournalInternational Journal of Surgical Pathology
- Malignant monotypic epithelioid angiomyolipoma of the retroperitoneum.
- Authors: Lau SK, Marchevsky AM, McKenna RJ Jr, Luthringer DJ
- Issue date: 2003 Jul
- Monotypic epithelioid angiomyolipoma of the liver.
- Authors: Yamasaki S, Tanaka S, Fujii H, Matsumoto T, Okuda C, Watanabe G, Suda K
- Issue date: 2000 May
- Angiomyolipoma of the nasal cavity.
- Authors: Tardío JC, Martín-Fragueiro LM
- Issue date: 2002 Aug
- Mucocutaneous angiomyolipoma. A report of 2 cases arising in the nasal cavity.
- Authors: Watanabe K, Suzuki T
- Issue date: 1999 Sep
- [Epithelioid angiomyolipoma of kidney: clinicopathologic study of two cases and review of literature].
- Authors: Meng YH, Pei F, Lu P, Yu JY, Zheng J
- Issue date: 2007 Jan