• Login
    View Item 
    •   Home
    • The Manchester Institute Cancer Research UK
    • All Paterson Institute for Cancer Research
    • View Item
    •   Home
    • The Manchester Institute Cancer Research UK
    • All Paterson Institute for Cancer Research
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

    All of ChristieCommunitiesTitleAuthorsIssue DateSubmit DateSubjectsThis CollectionTitleAuthorsIssue DateSubmit DateSubjectsProfilesView

    My Account

    LoginRegister

    Local Links

    The Christie WebsiteChristie Library and Knowledge Service

    Statistics

    Display statistics

    Characterization of an Epstein-Barr virus-related gammaherpesvirus from common marmoset (Callithrix jacchus).

    • CSV
    • RefMan
    • EndNote
    • BibTex
    • RefWorks
    Authors
    Jenson, Hal B
    Ench, Yasmin
    Zhang, Yanjin
    Gao, Shou-Jiang
    Arrand, John R
    Mackett, Mike
    Affiliation
    Department of Pediatrics, The University of Texas Health Science Center, 7703 Floyd Curl Drive, San Antonio, TX 78229-3900, USA. jenson@uthscsa.edu
    Issue Date
    2002-07
    
    Metadata
    Show full item record
    Abstract
    A gammaherpesvirus related to Epstein-Barr virus (EBV; Human herpesvirus 4) infects otherwise healthy common marmosets (Callithrix jacchus). Long-term culture of common marmoset peripheral blood lymphocytes resulted in outgrowth of spontaneously immortalized lymphoblastoid cell lines, primarily of B cell lineage. Electron microscopy of cells and supernatants showed herpesvirus particles. There were high rates of serological cross-reactivity to other herpesviruses (68-86%), but with very low geometric mean antibody titres [1:12 to human herpesvirus 6 and 1:14 to Herpesvirus papio (Cercopithecine herpesvirus 12)]. Sequence analysis of the conserved herpesvirus DNA polymerase gene showed that the virus is a member of the lymphocryptovirus subgroup and is most closely related to a lymphocryptovirus from rhesus macaques and is closely related to EBV and Herpesvirus papio. High seroprevalence (79%, with geometric mean antibody titre of 1:110) among 28 common marmosets from two geographically distinct colonies indicated that the virus is likely present in many common marmosets in captivity. A New World primate harbouring a lymphocryptovirus suggests that this subgroup arose much earlier than previously thought.
    Citation
    Characterization of an Epstein-Barr virus-related gammaherpesvirus from common marmoset (Callithrix jacchus). 2002, 83 (Pt 7):1621-33 J. Gen. Virol.
    Journal
    The Journal of General Virology
    URI
    http://hdl.handle.net/10541/82462
    PubMed ID
    12075080
    Type
    Article
    Language
    en
    ISSN
    0022-1317
    Collections
    All Paterson Institute for Cancer Research

    entitlement

    Related articles

    • Fatal lymphoproliferative disease associated with a novel gammaherpesvirus in a captive population of common marmosets.
    • Authors: Ramer JC, Garber RL, Steele KE, Boyson JF, O'Rourke C, Thomson JA
    • Issue date: 2000 Feb
    • An Epstein-Barr-related herpesvirus from marmoset lymphomas.
    • Authors: Cho Y, Ramer J, Rivailler P, Quink C, Garber RL, Beier DR, Wang F
    • Issue date: 2001 Jan 30
    • Complete genomic sequence of an Epstein-Barr virus-related herpesvirus naturally infecting a new world primate: a defining point in the evolution of oncogenic lymphocryptoviruses.
    • Authors: Rivailler P, Cho YG, Wang F
    • Issue date: 2002 Dec
    • Reduced prevalence of Epstein-Barr virus-related lymphocryptovirus infection in sera from a new world primate.
    • Authors: Fogg MH, Carville A, Cameron J, Quink C, Wang F
    • Issue date: 2005 Aug
    • Orangutan herpesvirus.
    • Authors: Sakulwira K, Theamboonlers A, Oraveerakul K, Chaiyabutr N, Bhattarakosol P, Poovorawan Y
    • Issue date: 2004 Feb
    DSpace software (copyright © 2002 - 2025)  DuraSpace
    Quick Guide | Contact Us
    Open Repository is a service operated by 
    Atmire NV
     

    Export search results

    The export option will allow you to export the current search results of the entered query to a file. Different formats are available for download. To export the items, click on the button corresponding with the preferred download format.

    By default, clicking on the export buttons will result in a download of the allowed maximum amount of items.

    To select a subset of the search results, click "Selective Export" button and make a selection of the items you want to export. The amount of items that can be exported at once is similarly restricted as the full export.

    After making a selection, click one of the export format buttons. The amount of items that will be exported is indicated in the bubble next to export format.