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    Cellular vaccine therapy for cancer.

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    Authors
    Armstrong, Anne C
    Eaton, David
    Ewing, Joanne
    Affiliation
    Department of Medical Oncology, Paterson Institute of Cancer Research, Christie Hospital NHS Trust, Manchester, UK. Aarmstrong@picr.man.ac.uk
    Issue Date
    2002-10
    
    Metadata
    Show full item record
    Abstract
    Observations that cells of the immune system are able to kill tumor cells both in vitro and in animal models have provided a compelling rationale for pursuit of a strategy whereby immune cells are administered as a therapeutic vaccine to patients with cancer. The successful outcome of this approach depends upon the ability to deliver this therapy in a manner in which a potent immune response is elicited. By harnessing the capacity of dendritic cells that are pivotal in priming the immune response and using gene therapy approaches to optimise the immune response, this may ultimately prove efficacious in the management of human cancer. Promising reports from recent clinical trials suggest that this may well be a realistic goal.
    Citation
    Cellular vaccine therapy for cancer. 2002, 1 (3):303-16 Expert Rev Vaccines
    Journal
    Expert Review of Vaccines
    URI
    http://hdl.handle.net/10541/82434
    DOI
    10.1586/14760584.1.3.303
    PubMed ID
    12901571
    Type
    Article
    Language
    en
    ISSN
    1476-0584
    ae974a485f413a2113503eed53cd6c53
    10.1586/14760584.1.3.303
    Scopus Count
    Collections
    All Paterson Institute for Cancer Research

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