Affiliation
Department of Medical Oncology, Paterson Institute of Cancer Research, Christie Hospital NHS Trust, Manchester, UK. Aarmstrong@picr.man.ac.ukIssue Date
2002-10
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Show full item recordAbstract
Observations that cells of the immune system are able to kill tumor cells both in vitro and in animal models have provided a compelling rationale for pursuit of a strategy whereby immune cells are administered as a therapeutic vaccine to patients with cancer. The successful outcome of this approach depends upon the ability to deliver this therapy in a manner in which a potent immune response is elicited. By harnessing the capacity of dendritic cells that are pivotal in priming the immune response and using gene therapy approaches to optimise the immune response, this may ultimately prove efficacious in the management of human cancer. Promising reports from recent clinical trials suggest that this may well be a realistic goal.Citation
Cellular vaccine therapy for cancer. 2002, 1 (3):303-16 Expert Rev VaccinesJournal
Expert Review of VaccinesDOI
10.1586/14760584.1.3.303PubMed ID
12901571Type
ArticleLanguage
enISSN
1476-0584ae974a485f413a2113503eed53cd6c53
10.1586/14760584.1.3.303
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