Affiliation
Department of Endocrinology, Christie Hospital, Manchester, UK.Issue Date
1999-10
Metadata
Show full item recordAbstract
Knowledge of the interaction between growth hormone (GH) and the growth hormone receptor (GHR) has led to the rational design of a GHR antagonist. An analogue of GH able to block the action of GH at the cellular level offers greater specificity of effect compared with current medical therapies and is not dependent on tumour characteristics. This chapter reviews the interaction between GH and the GHR, and discusses the outstanding issues regarding GHR antagonist therapy in acromegaly.Citation
Growth hormone receptor antagonists therapy for acromegaly. 1999, 13 (3):419-30 Baillieres Best Pract Res Clin Endocrinol MetabJournal
Baillière's Best Practice & Research. Clinical Endocrinology & MetabolismPubMed ID
10909433Type
ArticleLanguage
enCollections
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