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dc.contributor.authorDavis, Julian R E
dc.contributor.authorTrainer, Peter J
dc.date.accessioned2009-09-07T16:25:12Z
dc.date.available2009-09-07T16:25:12Z
dc.date.issued2002-12
dc.identifier.citationPituitary tumour therapy: using the biology. 2002, 14 (12):1p following 978 J. Neuroendocrinol.en
dc.identifier.issn0953-8194
dc.identifier.pmid12521030
dc.identifier.urihttp://hdl.handle.net/10541/80151
dc.description.abstractPituitary tumours are benign but cause significant problems, both because of their compressive effects on brain structures and also because of the syndromes of hormone excess or deficiency that they can cause. Endocrine therapy has become increasingly successful, with the development of dopamine agonists and somatostatin analogues. Recently growth hormone receptor antagonists have been developed by modification of the GH molecule. It is likely that further advances based on our understanding of the biology will dramatically improve the treatment of these tumours.
dc.language.isoenen
dc.subjectPituitary Canceren
dc.subject.meshAntineoplastic Agents, Hormonal
dc.subject.meshGene Therapy
dc.subject.meshHumans
dc.subject.meshPituitary Neoplasms
dc.titlePituitary tumour therapy: using the biology.en
dc.typeArticleen
dc.contributor.departmentDepartment of Endocrinology, Manchester Royal Infirmary &Christie Hospital, Manchester, UK.en
dc.identifier.journalJournal of Neuroendocrinologyen
html.description.abstractPituitary tumours are benign but cause significant problems, both because of their compressive effects on brain structures and also because of the syndromes of hormone excess or deficiency that they can cause. Endocrine therapy has become increasingly successful, with the development of dopamine agonists and somatostatin analogues. Recently growth hormone receptor antagonists have been developed by modification of the GH molecule. It is likely that further advances based on our understanding of the biology will dramatically improve the treatment of these tumours.


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