AffiliationDepartment of Endocrinology, Christie Hospital NHS Trust, Manchester, UK. email@example.com
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AbstractCancer may impinge on puberty either directly through a mass lesion effect on the reproductive axis or indirectly through hormones secreted by tumours, for example human chorionic gonadotrophin, or weight loss, or the actual presence of a chronic disease process per se. The more frequent pubertal problems faced by children with cancer are due to the impact of treatment either on the central nervous system, the hypothalamic-pituitary axis or the gonad; in this review, we concentrate on these complications and their potential management.
CitationPuberty in children with cancer. 2002, 57 Suppl 2:39-42 Horm. Res.
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