International expert panel on the use of primary (preoperative) systemic treatment of operable breast cancer: review and recommendations.
Von Minckwitz, Gunter
Costa, Serban Dan
Tulusan, Augustinos H
AffiliationDepartment of Gynecology and Obstetrics, Goethe University, Frankfurt am Main, Germany. M.Kaufmann@em.uni-frankfurt.de
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AbstractPrimary systemic therapy (PST) represents the standard of care in patients with locally advanced breast cancer. In addition, there is increasing information on PST in operable breast disease that supports the use of PST in routine practice. However, current regimens and techniques vary. To address this concern, a group of representatives from breast cancer clinical research groups in France, Germany, Italy, the United Kingdom, and the United States reviewed all available data on prospective randomized trials in this setting. Recommendations are made regarding terminology, indications, regimen, diagnosis before treatment, monitoring of efficacy, tumor localization, surgery, pathologic evaluation, and postoperative treatment.
CitationInternational expert panel on the use of primary (preoperative) systemic treatment of operable breast cancer: review and recommendations. 2003, 21 (13):2600-8 J. Clin. Oncol.
JournalJournal of Clinical Oncology
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