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    Skeletal requirements for optimal growth hormone replacement in the transitional years.

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    Authors
    Mukherjee, Annice
    Attanasio, Andrea F
    Shalet, Stephen M
    Affiliation
    Department of Endocrinology, Christie Hospital, Wilmslow Road, Withington, Manchester, UK. stephen.m.shalet@man.ac.uk
    Issue Date
    2003-08
    
    Metadata
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    Abstract
    In addition to its well-established effects on linear growth in childhood and adolescence, growth hormone (GH) has both direct and indirect actions on bone remodelling and homeostasis. In this review, the discussion begins with the influence of childhood-onset growth hormone deficiency (CO-GHD) on bone mineral accretion. The limitations of methods of assessing bone mineral density (BMD) are highlighted and specific influential factors, which affect peak bone mass achievement and therefore skeletal health in later life, are evaluated.
    Citation
    Skeletal requirements for optimal growth hormone replacement in the transitional years. 2003, 13 Suppl A:S130-5 Growth Horm. IGF Res.
    Journal
    Growth Hormone & IGF Research
    URI
    http://hdl.handle.net/10541/78977
    DOI
    10.1016/S1096-6374(03)00069-8
    PubMed ID
    12914741
    Type
    Article
    Language
    en
    ISSN
    1096-6374
    ae974a485f413a2113503eed53cd6c53
    10.1016/S1096-6374(03)00069-8
    Scopus Count
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