• Login
    View Item 
    •   Home
    • The Manchester Institute Cancer Research UK
    • All Paterson Institute for Cancer Research
    • View Item
    •   Home
    • The Manchester Institute Cancer Research UK
    • All Paterson Institute for Cancer Research
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

    All of ChristieCommunitiesTitleAuthorsIssue DateSubmit DateSubjectsThis CollectionTitleAuthorsIssue DateSubmit DateSubjects

    My Account

    LoginRegister

    Local Links

    The Christie WebsiteChristie Library and Knowledge Service

    Statistics

    Display statistics

    Assessment of therapeutic response in patients with metastatic bone disease.

    • CSV
    • RefMan
    • EndNote
    • BibTex
    • RefWorks
    Authors
    Clamp, Andrew R
    Danson, Sarah
    Nguyen, Huy
    Cole, David
    Clemons, Mark
    Affiliation
    Cancer Research UK, Department of Medical Oncology, Christie Hospital, Manchester, UK.
    Issue Date
    2004-10
    
    Metadata
    Show full item record
    Abstract
    Metastatic bone disease is common in cancer patients and causes substantial disease-related morbidity and mortality. However, several effective treatments are available for the management of these patients. Bisphosphonates, which inhibit osteoclast-mediated resorption of bone matrix, are especially important because they decrease the incidence of skeletal-related events in many tumour types and can complement antineoplastic therapies. At present, assessment of treatment for bone metastases is hindered by a lack of effective, rapid methods to measure disease response. We discuss the difficulties of current measures of response assessment and describe the development of new radiological and biochemical markers of bone metastases. Assays that detect type I collagen telopeptides as markers of bone resorption seem to be most promising at present.
    Citation
    Assessment of therapeutic response in patients with metastatic bone disease. 2004, 5 (10):607-16 Lancet Oncol.
    Journal
    The Lancet Oncology
    URI
    http://hdl.handle.net/10541/78441
    DOI
    10.1016/S1470-2045(04)01596-7
    PubMed ID
    15465464
    Type
    Article
    Language
    en
    ISSN
    1470-2045
    ae974a485f413a2113503eed53cd6c53
    10.1016/S1470-2045(04)01596-7
    Scopus Count
    Collections
    All Paterson Institute for Cancer Research

    entitlement

    Related articles

    • Clinical trials in metastatic breast cancer to bone: past--present--future.
    • Authors: Body JJ
    • Issue date: 1995 Dec
    • Bone imaging in metastatic breast cancer.
    • Authors: Hamaoka T, Madewell JE, Podoloff DA, Hortobagyi GN, Ueno NT
    • Issue date: 2004 Jul 15
    • The use of molecular markers of bone turnover in the management of patients with metastatic bone disease.
    • Authors: Seibel MJ
    • Issue date: 2008 Jun
    • The changing landscape of the medical management of skeletal metastases in nonsmall cell lung cancer.
    • Authors: Kosteva J, Langer C
    • Issue date: 2008 Mar
    • Diagnosis of skeletal metastases and assessment of response to treatment.
    • Authors: Galasko CS
    • Issue date: 1995 Mar
    DSpace software (copyright © 2002 - 2023)  DuraSpace
    Quick Guide | Contact Us
    Open Repository is a service operated by 
    Atmire NV
     

    Export search results

    The export option will allow you to export the current search results of the entered query to a file. Different formats are available for download. To export the items, click on the button corresponding with the preferred download format.

    By default, clicking on the export buttons will result in a download of the allowed maximum amount of items.

    To select a subset of the search results, click "Selective Export" button and make a selection of the items you want to export. The amount of items that can be exported at once is similarly restricted as the full export.

    After making a selection, click one of the export format buttons. The amount of items that will be exported is indicated in the bubble next to export format.