Show simple item record

dc.contributor.authorPereira, Gislene
dc.contributor.authorSchiebel, Elmar
dc.date.accessioned2009-08-24T14:12:38Z
dc.date.available2009-08-24T14:12:38Z
dc.date.issued2004-06
dc.identifier.citationCdc14 phosphatase resolves the rDNA segregation delay. 2004, 6 (6):473-5 Nat. Cell Biol.en
dc.identifier.issn1465-7392
dc.identifier.pmid15170454
dc.identifier.doi10.1038/ncb0604-473
dc.identifier.urihttp://hdl.handle.net/10541/78376
dc.description.abstractSister chromatid segregation in anaphase of mitosis is initiated through cleavage of cohesin by the protease separase. Two studies now show that this view is valid for most chromosomal DNA, but not for the highly repetitive ribosomal DNA (rDNA) and telomeres. The disjunction of these regions of the chromosome occurs in mid-anaphase, long after cohesin cleavage, and is regulated by the conserved phosphatase Cdc14.
dc.language.isoenen
dc.subject.meshAnaphase
dc.subject.meshCell Cycle Proteins
dc.subject.meshChromosome Segregation
dc.subject.meshDNA, Ribosomal
dc.subject.meshMitosis
dc.subject.meshProtein Tyrosine Phosphatases
dc.subject.meshSaccharomyces cerevisiae
dc.subject.meshSaccharomyces cerevisiae Proteins
dc.subject.meshTelomere
dc.titleCdc14 phosphatase resolves the rDNA segregation delay.en
dc.typeArticleen
dc.identifier.journalNature Cell Biologyen
html.description.abstractSister chromatid segregation in anaphase of mitosis is initiated through cleavage of cohesin by the protease separase. Two studies now show that this view is valid for most chromosomal DNA, but not for the highly repetitive ribosomal DNA (rDNA) and telomeres. The disjunction of these regions of the chromosome occurs in mid-anaphase, long after cohesin cleavage, and is regulated by the conserved phosphatase Cdc14.


This item appears in the following Collection(s)

Show simple item record