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    Cdc14 phosphatase resolves the rDNA segregation delay.

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    Authors
    Pereira, Gislene
    Schiebel, Elmar
    Issue Date
    2004-06
    
    Metadata
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    Abstract
    Sister chromatid segregation in anaphase of mitosis is initiated through cleavage of cohesin by the protease separase. Two studies now show that this view is valid for most chromosomal DNA, but not for the highly repetitive ribosomal DNA (rDNA) and telomeres. The disjunction of these regions of the chromosome occurs in mid-anaphase, long after cohesin cleavage, and is regulated by the conserved phosphatase Cdc14.
    Citation
    Cdc14 phosphatase resolves the rDNA segregation delay. 2004, 6 (6):473-5 Nat. Cell Biol.
    Journal
    Nature Cell Biology
    URI
    http://hdl.handle.net/10541/78376
    DOI
    10.1038/ncb0604-473
    PubMed ID
    15170454
    Type
    Article
    Language
    en
    ISSN
    1465-7392
    ae974a485f413a2113503eed53cd6c53
    10.1038/ncb0604-473
    Scopus Count
    Collections
    All Paterson Institute for Cancer Research

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