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dc.contributor.authorGoyal, Shama
dc.contributor.authorRoscoe, J
dc.contributor.authorRyder, W David J
dc.contributor.authorGattamaneni, Rao
dc.contributor.authorEden, Tim O B
dc.date.accessioned2009-08-20T13:00:23Z
dc.date.available2009-08-20T13:00:23Z
dc.date.issued2004-10
dc.identifier.citationSymptom interval in young people with bone cancer. 2004, 40 (15):2280-6 Eur. J. Canceren
dc.identifier.issn0959-8049
dc.identifier.pmid15454254
dc.identifier.doi10.1016/j.ejca.2004.05.017
dc.identifier.urihttp://hdl.handle.net/10541/78034
dc.description.abstractSymptom interval (SI), the time from first symptom/sign to diagnosis and initiation of treatment, appears to be principally influenced by tumour biology. Whether the age of the patient, patient delay, professional delay and access to health professionals influences the SI in bone tumours was investigated in this study. 115 patients with newly diagnosed osteosarcoma and Ewing's sarcoma were retrospectively reviewed. The median total SI for all bone tumours was 3.8 months (range 1-46 months). Patients older than 12 years had a longer SI (P = 0.05) and more patient delays (P = 0.02). Total SI and professional delays were longer if the General Practitioner was first seen compared with an Accident and Emergency Consultant (P = 0.02 and 0.02, respectively). However, SI did not influence overall and event-free survival in this series. Bone tumour patients have long SIs that are significantly affected by age and local health-care support systems. Early referral to specialists would help to alleviate anxiety and distress to the patient and family, even if currently delay does not influence outcome.
dc.language.isoenen
dc.subjectBone Canceren
dc.subject.meshAdolescent
dc.subject.meshAdult
dc.subject.meshBone Neoplasms
dc.subject.meshChild
dc.subject.meshChild, Preschool
dc.subject.meshEarly Diagnosis
dc.subject.meshFamily Practice
dc.subject.meshFemale
dc.subject.meshHumans
dc.subject.meshMale
dc.subject.meshOsteosarcoma
dc.subject.meshPatient Acceptance of Health Care
dc.subject.meshReferral and Consultation
dc.subject.meshRetrospective Studies
dc.subject.meshSarcoma, Ewing's
dc.subject.meshSurvival Analysis
dc.subject.meshTime Factors
dc.titleSymptom interval in young people with bone cancer.en
dc.typeArticleen
dc.contributor.departmentYoung Oncology Unit, Christie Hospital, Wilmslow Road, Manchester M20 4BX, UK.en
dc.identifier.journalEuropean Journal of Canceren
html.description.abstractSymptom interval (SI), the time from first symptom/sign to diagnosis and initiation of treatment, appears to be principally influenced by tumour biology. Whether the age of the patient, patient delay, professional delay and access to health professionals influences the SI in bone tumours was investigated in this study. 115 patients with newly diagnosed osteosarcoma and Ewing's sarcoma were retrospectively reviewed. The median total SI for all bone tumours was 3.8 months (range 1-46 months). Patients older than 12 years had a longer SI (P = 0.05) and more patient delays (P = 0.02). Total SI and professional delays were longer if the General Practitioner was first seen compared with an Accident and Emergency Consultant (P = 0.02 and 0.02, respectively). However, SI did not influence overall and event-free survival in this series. Bone tumour patients have long SIs that are significantly affected by age and local health-care support systems. Early referral to specialists would help to alleviate anxiety and distress to the patient and family, even if currently delay does not influence outcome.


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