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dc.contributor.authorBlackhall, Fiona H
dc.contributor.authorShepherd, Frances A
dc.date.accessioned2009-08-20T10:36:51Z
dc.date.available2009-08-20T10:36:51Z
dc.date.issued2004-10
dc.identifier.citationAngiogenesis inhibitors in the treatment of small cell and non-small cell lung cancer. 2004, 18 (5):1121-41, Hematol. Oncol. Clin. North Am.en
dc.identifier.issn0889-8588
dc.identifier.pmid15474338
dc.identifier.doi10.1016/j.hoc.2004.06.005
dc.identifier.urihttp://hdl.handle.net/10541/77985
dc.description.abstractAngiogenesis is believed to play a critical role in cancer; however, antiangiogenic therapy has not been demonstrated to improve the survival of patients who have lung cancer. In this article, the evidence that supports a role for angiogenesis in the pathogenesis of lung cancer, trials of antiangiogenic agents in lung cancer performed to date, and the lessons learned from these studies are discussed.
dc.language.isoenen
dc.subjectLung Canceren
dc.subject.meshAngiogenesis Inhibitors
dc.subject.meshCarcinoma, Non-Small-Cell Lung
dc.subject.meshCarcinoma, Small Cell
dc.subject.meshClinical Trials as Topic
dc.subject.meshHumans
dc.subject.meshLung Neoplasms
dc.subject.meshNeovascularization, Pathologic
dc.subject.meshProtease Inhibitors
dc.subject.meshVascular Endothelial Growth Factor A
dc.titleAngiogenesis inhibitors in the treatment of small cell and non-small cell lung cancer.en
dc.typeArticleen
dc.contributor.departmentDepartment of Medical Oncology, Christie Hospital NHS Trust, Wilmslow Road, Manchester, M20 4BX England, UK.en
dc.identifier.journalHematology/Oncology Clinics of North Americaen
html.description.abstractAngiogenesis is believed to play a critical role in cancer; however, antiangiogenic therapy has not been demonstrated to improve the survival of patients who have lung cancer. In this article, the evidence that supports a role for angiogenesis in the pathogenesis of lung cancer, trials of antiangiogenic agents in lung cancer performed to date, and the lessons learned from these studies are discussed.


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