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dc.contributor.authorHowell, Anthony
dc.date.accessioned2009-08-19T14:34:59Z
dc.date.available2009-08-19T14:34:59Z
dc.date.issued2004
dc.identifier.citationAn early peak of relapse after surgery for breast cancer. 2004, 6 (6):255-7 Breast Cancer Res.en
dc.identifier.issn1465-542X
dc.identifier.pmid15535855
dc.identifier.doi10.1186/bcr946
dc.identifier.urihttp://hdl.handle.net/10541/77872
dc.description.abstractThere is great interest among oncologists concerning what we might learn by examining the pattern of relapse after breast cancer surgery. What you see depends upon how hard you look. Up to now, investigators have examined the hazard ratio for relapse every 6-12 months. In a research paper, published in this issue of Breast Cancer Research, the Milan group have looked at the hazard ratio every three months and have found, for the first time, a distinct, very early peak of relapse in a group of premenopausal, node-positive patients not given chemotherapy or hormone therapy. What is now needed is for other groups to repeat this observation and, if found, to examine the characteristics of the tumours producing this phenomenon in order to develop hypotheses about its cause and possible treatments.
dc.language.isoenen
dc.subjectBreast Canceren
dc.subjectCancer Recurrenceen
dc.subject.meshBreast Neoplasms
dc.subject.meshFemale
dc.subject.meshHumans
dc.subject.meshNeoplasm Recurrence, Local
dc.subject.meshProportional Hazards Models
dc.subject.meshTime Factors
dc.titleAn early peak of relapse after surgery for breast cancer.en
dc.typeArticleen
dc.contributor.departmentCRUK Department of Medical Oncology, Christie Hospital, University of Manchester, Manchester, UK. Anthony.Howell@christie-tr.nwest.nhs.uken
dc.identifier.journalBreast Cancer Researchen
html.description.abstractThere is great interest among oncologists concerning what we might learn by examining the pattern of relapse after breast cancer surgery. What you see depends upon how hard you look. Up to now, investigators have examined the hazard ratio for relapse every 6-12 months. In a research paper, published in this issue of Breast Cancer Research, the Milan group have looked at the hazard ratio every three months and have found, for the first time, a distinct, very early peak of relapse in a group of premenopausal, node-positive patients not given chemotherapy or hormone therapy. What is now needed is for other groups to repeat this observation and, if found, to examine the characteristics of the tumours producing this phenomenon in order to develop hypotheses about its cause and possible treatments.


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