An early peak of relapse after surgery for breast cancer.

Howell, Anthony

dc.contributor.author	Howell, Anthony
dc.date.accessioned	2009-08-19T14:34:59Z
dc.date.available	2009-08-19T14:34:59Z
dc.date.issued	2004
dc.identifier.citation	An early peak of relapse after surgery for breast cancer. 2004, 6 (6):255-7 Breast Cancer Res.	en
dc.identifier.issn	1465-542X
dc.identifier.pmid	15535855
dc.identifier.doi	10.1186/bcr946
dc.identifier.uri	http://hdl.handle.net/10541/77872
dc.description.abstract	There is great interest among oncologists concerning what we might learn by examining the pattern of relapse after breast cancer surgery. What you see depends upon how hard you look. Up to now, investigators have examined the hazard ratio for relapse every 6-12 months. In a research paper, published in this issue of Breast Cancer Research, the Milan group have looked at the hazard ratio every three months and have found, for the first time, a distinct, very early peak of relapse in a group of premenopausal, node-positive patients not given chemotherapy or hormone therapy. What is now needed is for other groups to repeat this observation and, if found, to examine the characteristics of the tumours producing this phenomenon in order to develop hypotheses about its cause and possible treatments.
dc.language.iso	en	en
dc.subject	Breast Cancer	en
dc.subject	Cancer Recurrence	en
dc.subject.mesh	Breast Neoplasms
dc.subject.mesh	Female
dc.subject.mesh	Humans
dc.subject.mesh	Neoplasm Recurrence, Local
dc.subject.mesh	Proportional Hazards Models
dc.subject.mesh	Time Factors
dc.title	An early peak of relapse after surgery for breast cancer.	en
dc.type	Article	en
dc.contributor.department	CRUK Department of Medical Oncology, Christie Hospital, University of Manchester, Manchester, UK. Anthony.Howell@christie-tr.nwest.nhs.uk	en
dc.identifier.journal	Breast Cancer Research	en
refterms.dateFOA	2020-06-18T14:18:43Z
html.description.abstract	There is great interest among oncologists concerning what we might learn by examining the pattern of relapse after breast cancer surgery. What you see depends upon how hard you look. Up to now, investigators have examined the hazard ratio for relapse every 6-12 months. In a research paper, published in this issue of Breast Cancer Research, the Milan group have looked at the hazard ratio every three months and have found, for the first time, a distinct, very early peak of relapse in a group of premenopausal, node-positive patients not given chemotherapy or hormone therapy. What is now needed is for other groups to repeat this observation and, if found, to examine the characteristics of the tumours producing this phenomenon in order to develop hypotheses about its cause and possible treatments.