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    Regressed cutaneous malignant melanoma mimicking lymphoma: a potential diagnostic pitfall.

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    Authors
    Menasce, Lia P
    Shanks, Jonathan H
    Howarth, V S
    Banerjee, Saumitra S
    Affiliation
    Department of Pathology, Christie Hospital NHS Trust, Withington, Manchester, UK.
    Issue Date
    2005-07
    
    Metadata
    Show full item record
    Abstract
    We report 2 cases of partially regressed malignant melanoma in which the brisk lymphocytic response closely resembled mycosis fungoides in 1 case and nodular sclerosing Hodgkin lymphoma in the other. Striking epidermotropism was present in both cases. The lymphocytes were predominantly of T8 cytotoxic subtype, and oligoclonal T-cell expansion was detected in 1 of the cases. The scanty residual melanoma cells were highlighted with HMB45 and S100 protein. We highlight the features of regression in melanoma that may lead to an erroneous diagnosis of lymphoma and discuss the finding of oligoclonal T-cell expansion in regressed melanocytic lesions.
    Citation
    Regressed cutaneous malignant melanoma mimicking lymphoma: a potential diagnostic pitfall. 2005, 13 (3):281-4 Int. J. Surg. Pathol.
    Journal
    International Journal of Surgical Pathology
    URI
    http://hdl.handle.net/10541/76780
    PubMed ID
    16086086
    Type
    Article
    Language
    en
    ISSN
    1066-8969
    Collections
    All Christie Publications

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