Pigmented mesenteric lymphadenopathy in familial adenomatous polyposis - an unusual cause of intraoperative abandonment of ileo-anal pouch.
Affiliation
Department of Surgery, Christie Hospital, Manchester, UK. nagarajan.pranesh@christie-tr.nwest.nhs.ukIssue Date
2005-07
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Show full item recordAbstract
Familial adenomatous polyposis (FAP) is an autosomal dominant condition with near complete penetrance, characterised by the presence of numerous adenomatous polyps of the colon and rectum. Melanosis coli describes the brownish-black discolouration of the colon resulting from the accumulation of a granular pigment in the phagosomes of macrophages in the colonic lamina propria. The presence of melanosis pigment in pericolonic lymph nodes has been reported in patients with coincidental melanosis coli, following segmental colonic resection. We report a unique case of FAP with melanosis pigment in lymph nodes in the small bowel mesentery that initially prevented a restorative proctocolectomy but that resolved following a colectomy, subsequently facilitating formation of an ileo-anal pouch.Citation
Pigmented mesenteric lymphadenopathy in familial adenomatous polyposis - an unusual cause of intraoperative abandonment of ileo-anal pouch. 2005, 87 (4):W1-4 Ann R Coll Surg EnglJournal
Annals of the Royal College of Surgeons of EnglandDOI
10.1308/147870805X50708PubMed ID
16884599Type
ArticleLanguage
enISSN
0035-8843ae974a485f413a2113503eed53cd6c53
10.1308/147870805X50708