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    Mechanisms of improved survival from intensive followup in colorectal cancer: a hypothesis.

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    Authors
    Renehan, Andrew G
    Egger, Matthias
    Saunders, Mark P
    O'Dwyer, Sarah T
    Affiliation
    Department of Surgery, Christie Hospital NHS Trust, Wilmslow Road, Manchester M20 4BX, UK. arenehan@picr.man.ac.uk
    Issue Date
    2005-02-14
    
    Metadata
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    Abstract
    A meta-analysis of six randomised trials demonstrated that intensive followup in colorectal cancer was associated with an absolute reduction in all-cause 5-year mortality of 10% (95% confidence interval (CI): 4-16)--however, only two percent (95% CI: 0-5) was attributable to cure from salvage re-operations. We postulate that other factors, such as increased psychological well-being and/or altered lifestyle, and/or improved treatment of coincidental disease may contribute to the remaining lives saved, and form important future research questions.
    Citation
    Mechanisms of improved survival from intensive followup in colorectal cancer: a hypothesis. 2005, 92 (3):430-3 Br. J. Cancer
    Journal
    British Journal of Cancer
    URI
    http://hdl.handle.net/10541/75801
    DOI
    10.1038/sj.bjc.6602369
    PubMed ID
    15685236
    Type
    Article
    Language
    en
    ISSN
    0007-0920
    ae974a485f413a2113503eed53cd6c53
    10.1038/sj.bjc.6602369
    Scopus Count
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