Mechanisms of improved survival from intensive followup in colorectal cancer: a hypothesis.
AffiliationDepartment of Surgery, Christie Hospital NHS Trust, Wilmslow Road, Manchester M20 4BX, UK. email@example.com
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AbstractA meta-analysis of six randomised trials demonstrated that intensive followup in colorectal cancer was associated with an absolute reduction in all-cause 5-year mortality of 10% (95% confidence interval (CI): 4-16)--however, only two percent (95% CI: 0-5) was attributable to cure from salvage re-operations. We postulate that other factors, such as increased psychological well-being and/or altered lifestyle, and/or improved treatment of coincidental disease may contribute to the remaining lives saved, and form important future research questions.
CitationMechanisms of improved survival from intensive followup in colorectal cancer: a hypothesis. 2005, 92 (3):430-3 Br. J. Cancer
JournalBritish Journal of Cancer
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