Sequential platinum-based chemotherapy-thoracic radiotherapy in early stage non-small cell lung cancer.
Affiliation
CRC Department of Medical Oncology, Christie Hospital NHS Trust, Wilmslow Road, Manchester M20 9BX, United Kingdom. nick.thatcher@christie-tr.nwest.nhs.ukIssue Date
2005-07-01
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Combined chemoradiotherapy (CTRT) is intended to reduce the risk of local regional recurrence and distant relapse in patients with early stage non-small cell lung cancer (NSCLC). Sequential CTRT allows full doses of each modality while avoiding the additive toxicity that occurs with concurrent therapy. This review will encompass studies in the three main settings where sequential CTRT has been applied in early stage NSCLC: as adjuvant therapy after resection, as neoadjuvant chemotherapy and surgery followed by radiotherapy, and in unresectable stage III disease.Citation
Sequential platinum-based chemotherapy-thoracic radiotherapy in early stage non-small cell lung cancer. 2005, 11 (13 Pt 2):5051s-5056s Clin. Cancer Res.Journal
Clinical Cancer ResearchDOI
10.1158/1078-0432.CCR-05-9004PubMed ID
16000613Type
ArticleLanguage
enISSN
1078-0432ae974a485f413a2113503eed53cd6c53
10.1158/1078-0432.CCR-05-9004
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