The prognostic value of pimonidazole and tumour pO2 in human cervix carcinomas after radiation therapy: a prospective international multi-center study.
Authors
Nordsmark, MarianneLoncaster, Juliette A
Aquino-Parsons, Christina
Chou, Shu-Chuan
Gebski, Val
West, Catharine M L
Lindegaard, Jacob C
Havsteen, Hanne
Davidson, Susan E
Hunter, Robin D
Raleigh, James A
Overgaard, Jens
Affiliation
Department of Experimental Clinical Oncology, Aarhus University Hospital, Denmark. marianne@oncology.dk <marianne@oncology.dk>Issue Date
2006-08
Metadata
Show full item recordAbstract
BACKGROUND AND PURPOSE: Hypoxia adversely affects treatment outcome in human uterine cervical cancer. Here, we present the results of a prospective international multi-centre study evaluating the prognostic value of pre-treatment tumour oxygen partial pressure (pO(2)) and the hypoxia marker pimonidazole (pimo). MATERIALS AND METHODS: One hundred and twenty-seven patients with primary cervix cancer were entered. Pre-treatment tumour pO(2) measurements were obtained, and reported by the median tumour pO(2), the fraction of pO(2) valuesCitation
The prognostic value of pimonidazole and tumour pO2 in human cervix carcinomas after radiation therapy: a prospective international multi-center study. 2006, 80 (2):123-31 Radiother OncolJournal
Radiotherapy and OncologyDOI
10.1016/j.radonc.2006.07.010PubMed ID
16890316Type
ArticleLanguage
enISSN
0167-8140ae974a485f413a2113503eed53cd6c53
10.1016/j.radonc.2006.07.010