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    The prognostic value of pimonidazole and tumour pO2 in human cervix carcinomas after radiation therapy: a prospective international multi-center study.

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    Authors
    Nordsmark, Marianne
    Loncaster, Juliette A
    Aquino-Parsons, Christina
    Chou, Shu-Chuan
    Gebski, Val
    West, Catharine M L
    Lindegaard, Jacob C
    Havsteen, Hanne
    Davidson, Susan E
    Hunter, Robin D
    Raleigh, James A
    Overgaard, Jens
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    Affiliation
    Department of Experimental Clinical Oncology, Aarhus University Hospital, Denmark. marianne@oncology.dk <marianne@oncology.dk>
    Issue Date
    2006-08
    
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    Abstract
    BACKGROUND AND PURPOSE: Hypoxia adversely affects treatment outcome in human uterine cervical cancer. Here, we present the results of a prospective international multi-centre study evaluating the prognostic value of pre-treatment tumour oxygen partial pressure (pO(2)) and the hypoxia marker pimonidazole (pimo). MATERIALS AND METHODS: One hundred and twenty-seven patients with primary cervix cancer were entered. Pre-treatment tumour pO(2) measurements were obtained, and reported by the median tumour pO(2), the fraction of pO(2) values
    Citation
    The prognostic value of pimonidazole and tumour pO2 in human cervix carcinomas after radiation therapy: a prospective international multi-center study. 2006, 80 (2):123-31 Radiother Oncol
    Journal
    Radiotherapy and Oncology
    URI
    http://hdl.handle.net/10541/72836
    DOI
    10.1016/j.radonc.2006.07.010
    PubMed ID
    16890316
    Type
    Article
    Language
    en
    ISSN
    0167-8140
    ae974a485f413a2113503eed53cd6c53
    10.1016/j.radonc.2006.07.010
    Scopus Count
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    All Christie Publications
    All Paterson Institute for Cancer Research

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