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    Recent developments in the therapy of acromegaly.

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    Authors
    Paisley, Angela N
    Trainer, Peter J
    Affiliation
    Department of Endocrinology, Christie Hospital, Manchester, M20 4BX, UK.
    Issue Date
    2006-03
    
    Metadata
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    Abstract
    Acromegaly, a condition due to growth hormone hypersecretion usually from a benign pituitary tumour, is associated with significant morbidity and mortality. Disease control leads to normalisation of life expectancy with a reduction in signs and symptoms. Treatment modalities include surgery, radiotherapy and medical management. Surgery is the primary treatment in most of the patients, with success rates of 61-91% reported for those with microadenomas who are operated on by a specialist pituitary surgeon; however, most patients have macroadenomas and, although benefiting from surgery, are not cured and require additional medical therapy. This review will focus on emerging concepts in the medical treatment of acromegaly.
    Citation
    Recent developments in the therapy of acromegaly. 2006, 15 (3):251-6 Expert Opin Investig Drugs
    Journal
    Expert Opinion on Investigational Drugs
    URI
    http://hdl.handle.net/10541/72638
    DOI
    10.1517/13543784.15.3.251
    PubMed ID
    16503762
    Type
    Article
    Language
    en
    ISSN
    1744-7658
    ae974a485f413a2113503eed53cd6c53
    10.1517/13543784.15.3.251
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