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    Pharmacogenetics in the management of breast cancer -- prospects for individualised treatment.

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    Authors
    Blackhall, Fiona H
    Howell, Sacha J
    Newman, Bill
    Affiliation
    Department of Medical Oncology, Christie Hospital NHS Trust, M20 2BX, Manchester, UK.
    Issue Date
    2006
    
    Metadata
    Show full item record
    Abstract
    Increased understanding of how variants in genes encoding metabolising enzymes, transporters and receptors affect drug efficacy and toxicity, in parallel with advances in genotyping technology means that clinical pharmacogenetics is drawing tantalisingly close to reality. This review considers some of the pharmacogenetic variants that have been described that are relevant to the management of women with breast cancer and how these may soon translate into clinical practice.
    Citation
    Pharmacogenetics in the management of breast cancer -- prospects for individualised treatment. 2006, 5 (2):151-7 Fam. Cancer
    Journal
    Familial Cancer
    URI
    http://hdl.handle.net/10541/72599
    DOI
    10.1007/s10689-005-3241-5
    PubMed ID
    16736284
    Type
    Article
    Language
    en
    ISSN
    1389-9600
    ae974a485f413a2113503eed53cd6c53
    10.1007/s10689-005-3241-5
    Scopus Count
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