Novel heparin/heparan sulfate mimics as inhibitors of HGF/SF-induced MET activation
Authors
Raiber, Eun-AngWilkinson, James A
Manetti, Fabrizio
Botta, Maurizio
Deakin, Jon A
Gallagher, John T
Lyon, Malcolm
Ducki, Sylvie W
Affiliation
Centre for Molecular Drug Design, Cockcroft Building, University of Salford, Salford, UK.Issue Date
2007-11-15
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Show full item recordAbstract
The synthesis of simple, non-sugar glycosaminoglycan (GAG) mimics has been achieved and the analogues evaluated for their ability to inhibit the activation of the MET receptor by hepatocyte growth factor/scatter factor (HGF/SF).Citation
Novel heparin/heparan sulfate mimics as inhibitors of HGF/SF-induced MET activation. 2007, 17 (22):6321-5 Bioorg. Med. Chem. Lett.Journal
Bioorganic & Medicinal Chemistry LettersDOI
10.1016/j.bmcl.2007.08.074PubMed ID
17870532Type
ArticleLanguage
enISSN
0960-894Xae974a485f413a2113503eed53cd6c53
10.1016/j.bmcl.2007.08.074
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