The management of cancer-related fatigue after chemotherapy with acupuncture and acupressure: a randomised controlled trial
AffiliationUniversity of Manchester, School of Nursing, Midwifery & Social Work, Coupland III, Coupland Street, Manchester M13 9PL, UK. firstname.lastname@example.org
MetadataShow full item record
AbstractBACKGROUND: Cancer-related fatigue after chemotherapy is a difficult symptom to manage in practice and the most disruptive symptom in patients' lives. Acupuncture is a popular complementary therapy among cancer patients and some evidence exists that it could potentially alleviate fatigue by stimulating 'energy' points in the body. Hence, this study was carried out to assess the effects of acupuncture and acupressure in managing cancer-related fatigue and the feasibility of running a randomised trial with these two complementary therapies in preparation for a large trial. METHODS: This study was a randomised controlled trial. Forty-seven patients with cancer who experienced moderate to severe fatigue were randomised either to an acupuncture group (n=15), an acupressure group (n=16) or a sham acupressure group (n=16). The acupuncture group received six 20-min sessions over 2 weeks, while the patients in the two acupressure groups were taught to massage/press the points and did so daily thereafter for 2 weeks on their own. Patients completed the Multidimensional Fatigue Inventory before randomisation, at the end of the 2-week intervention and again about 2 weeks after the end of the intervention. RESULTS: Significant improvements were found with regards to General fatigue (P<0.001), Physical fatigue (P=0.016), Activity (p=0.004) and Motivation (P=0.024). At the end of the intervention, there was a 36% improvement in fatigue levels in the acupuncture group, while the acupressure group improved by 19% and the sham acupressure by 0.6%. Improvements were observed even 2 weeks after treatments, although they were lower (22%, 15%, 7%, respectively). Acupuncture was a more effective method than acupressure or sham acupressure. Subjects needed a longer treatment period to have more sustained results. The trial was methodologically feasible. CONCLUSION: Acupuncture shows great potential in the management of cancer-related fatigue. As a randomised trial with acupuncture is feasible and preliminary data shows significant improvements, it should be tested further using a large sample and a multicentre design.
CitationThe management of cancer-related fatigue after chemotherapy with acupuncture and acupressure: a randomised controlled trial. 2007, 15 (4):228-37 Complement Ther Med
JournalComplementary Therapies in Medicine
- Pilot, randomized, modified, double-blind, placebo-controlled trial of acupuncture for cancer-related fatigue.
- Authors: Balk J, Day R, Rosenzweig M, Beriwal S
- Issue date: 2009 Winter
- Acupressure for smoking cessation--a pilot study.
- Authors: White AR, Moody RC, Campbell JL
- Issue date: 2007 Mar 14
- The efficacy of acupressure for decreasing agitated behaviour in dementia: a pilot study.
- Authors: Yang MH, Wu SC, Lin JG, Lin LC
- Issue date: 2007 Feb
- Implementation of acupuncture and acupressure under surgical procedures in children: a pilot study.
- Authors: Norheim AJ, Liodden I, Howley M
- Issue date: 2010 Jun
- Acupuncture for cancer-related fatigue in patients with breast cancer: a pragmatic randomized controlled trial.
- Authors: Molassiotis A, Bardy J, Finnegan-John J, Mackereth P, Ryder DW, Filshie J, Ream E, Richardson A
- Issue date: 2012 Dec 20