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    The genomics revolution and radiotherapy

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    Authors
    West, Catharine M L
    Elliott, Rebecca M
    Burnet, N G
    Affiliation
    Academic Radiation Oncology, University of Manchester, Christie Hospital NHS Trust, Manchester M20 4BX, UK. catharine.west@manchester.ac.uk
    Issue Date
    2007-08
    
    Metadata
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    Abstract
    The expansion of our knowledge through the Human Genome Project has been accompanied by the development of new high-throughput techniques, which provide extensive capabilities for the analysis of a large number of genes or the whole genome. These assays can be carried out in various clinical samples at the DNA (genome), RNA (transcriptome) or protein (proteome) level. There is a belief that this genomic revolution, i.e. sequencing of the human genome and developments in high-throughput technology, heralds a future of personalised medicine. For clinical oncology, this progress should increase the possibility of predicting individual patient responses to radiotherapy. This review highlights some of the work involving sparsely ionising radiation and the new technologies.
    Citation
    The genomics revolution and radiotherapy. 2007, 19 (6):470-80 Clin Oncol
    Journal
    Clinical Oncology
    URI
    http://hdl.handle.net/10541/70240
    DOI
    10.1016/j.clon.2007.02.016
    PubMed ID
    17419040
    Type
    Article
    Language
    en
    ISSN
    0936-6555
    ae974a485f413a2113503eed53cd6c53
    10.1016/j.clon.2007.02.016
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