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dc.contributor.authorEyden, Brian P
dc.date.accessioned2009-06-05T10:14:27Z
dc.date.available2009-06-05T10:14:27Z
dc.date.issued2009
dc.identifier.citationA structure resembling basal/external lamina on the surface of plasma cells, and a discussion on intercellular contacts between hemolymphoid cells., 33 (1):16-20 Ultrastruct Patholen
dc.identifier.issn1521-0758
dc.identifier.pmid19191197
dc.identifier.doi10.1080/01913120802636787
dc.identifier.urihttp://hdl.handle.net/10541/69782
dc.description.abstractBasal/external lamina is not found over plasma cells or other hemolymphoid cells, and the feature can have diagnostic value in distinguishing the neoplastic counterparts of such cells from epithelium, endothelium, mesothelium, and so on, which do have this feature. In this paper, a material ultrastructurally indistinguishable from basal or external lamina is reported on reactive plasma cells found in a fibrous pseudotumor, intralobular stroma of normal breast, tumor stroma of squamous cell carcinoma, and submucosa of normal human small intestine. It was focal, followed the contours of the cell-surface membrane, was lightly textured, 40-80 nm thick, and separated from the plasma cell surface membrane by a clear space resembling a lamina lucida. Its function remains uncertain, although it may implement adhesion to other cells, as part of the immune functions that plasma cells and other hemolymphoid cells perform in the gut, for example, and elsewhere.
dc.language.isoenen
dc.subjectBasal Laminaen
dc.subjectImmune Functionen
dc.subjectUltrastructureen
dc.subjectTumouren
dc.subject.meshBasement Membrane
dc.subject.meshBreast
dc.subject.meshCarcinoma, Squamous Cell
dc.subject.meshCell Communication
dc.subject.meshCell Membrane
dc.subject.meshFemale
dc.subject.meshGranuloma, Plasma Cell
dc.subject.meshHumans
dc.subject.meshIntestinal Mucosa
dc.subject.meshMicroscopy, Electron, Transmission
dc.subject.meshPlasma Cells
dc.titleA structure resembling basal/external lamina on the surface of plasma cells, and a discussion on intercellular contacts between hemolymphoid cells.en
dc.typeArticleen
dc.contributor.departmentDepartment of Histopathology, The Christie NHS Foundation Trust, Manchester, UK. brian.eyden@christie.nhs.uken
dc.identifier.journalUltrastructural Pathologyen
html.description.abstractBasal/external lamina is not found over plasma cells or other hemolymphoid cells, and the feature can have diagnostic value in distinguishing the neoplastic counterparts of such cells from epithelium, endothelium, mesothelium, and so on, which do have this feature. In this paper, a material ultrastructurally indistinguishable from basal or external lamina is reported on reactive plasma cells found in a fibrous pseudotumor, intralobular stroma of normal breast, tumor stroma of squamous cell carcinoma, and submucosa of normal human small intestine. It was focal, followed the contours of the cell-surface membrane, was lightly textured, 40-80 nm thick, and separated from the plasma cell surface membrane by a clear space resembling a lamina lucida. Its function remains uncertain, although it may implement adhesion to other cells, as part of the immune functions that plasma cells and other hemolymphoid cells perform in the gut, for example, and elsewhere.


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