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    Normal testicular function and spermatogenesis.

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    Authors
    Shalet, Stephen M
    Affiliation
    Department of Endocrinology, Christie Hospital, Manchester, England, UK.
    Issue Date
    2009-04-02
    
    Metadata
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    Abstract
    The testis performs two basic functions, sperm production and testosterone secretion. Formation of the testis is genetically controlled; expression of the SRY gene directs the embryonic gonads into the pathway leading to the development of testes. By the fourth week of gestation in humans, the primordial germ cells derived from pluripotent cells of the embryonic epiblast proliferate and migrate from the endoderm of the yolk sac into the undifferentiated gonad, which becomes morphologically distinct during the seventh week of gestation in humans. Histological development of the testis is largely completed by the end of the third month of gestation. Pediatr Blood Cancer (c) 2009 Wiley-Liss, Inc.
    Citation
    Normal testicular function and spermatogenesis. 2009: Pediatr Blood Cancer
    Journal
    Pediatric Blood & Cancer
    URI
    http://hdl.handle.net/10541/69714
    DOI
    10.1002/pbc.22000
    PubMed ID
    19343782
    Type
    Article
    Language
    en
    ISSN
    1545-5017
    ae974a485f413a2113503eed53cd6c53
    10.1002/pbc.22000
    Scopus Count
    Collections
    All Christie Publications
    Endocrinology

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