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    Testicular seminoma with mediastinal lymphadenopathy -- a diagnostic pitfall.

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    Authors
    Jegannathen, Apurna
    Taylor, Malcolm B
    Jones, M
    Logue, John P
    Affiliation
    Departments of Clinical Oncology, Christie Hospital NHS Foundation Trust, Manchester, UK.
    Issue Date
    2009-05
    
    Metadata
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    Abstract
    Relapse following adjuvant paraaortic radiation therapy in patients with Stage I seminoma is rare, occurring in approximately 4% of men. The majority of relapses are sited in the pelvis but relapse in the mediastinum is also recognised. As such, radiological imaging using chest radiographs remains commonplace in follow-up. However, there are reports of the association of testicular cancers with sarcoidosis and sarcoid-like processes in the mediastinum, emphasising the importance of making histological diagnosis prior to commencement of any treatment. We report on two men treated for testicular seminoma who on follow-up developed mediastinal lymphadenopathy, which was initially assumed to be metastatic seminoma. Both patients underwent mediastinascopy and biopsy prior to commencement of anti-cancer therapy. In both cases, the biopsies showed sarcoidosis, and unnecessary anti-cancer treatment was avoided.
    Citation
    Testicular seminoma with mediastinal lymphadenopathy -- a diagnostic pitfall. 2009, 82 (977):e85-6 Br J Radiol
    Journal
    The British Journal of Radiology
    URI
    http://hdl.handle.net/10541/69560
    DOI
    10.1259/bjr/40671180
    PubMed ID
    19386953
    Type
    Article
    Language
    en
    ISSN
    1748-880X
    ae974a485f413a2113503eed53cd6c53
    10.1259/bjr/40671180
    Scopus Count
    Collections
    All Christie Publications
    Radiology
    Clinical Oncology

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