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    Survival from cancer in teenagers and young adults in England, 1979-2003.

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    Authors
    Birch, Jillian M
    Pang, Dong
    Alston, Robert D
    Rowan, Steve
    Geraci, Marco
    Moran, Anthony
    Eden, Tim O B
    Affiliation
    Cancer Research UK, Paediatric and Familial Cancer Research Group, University of Manchester, Royal Manchester Children's Hospital, Stancliffe, Hospital Road, Manchester M27 4HA, UK. jillian.birch@manchester.ac.uk
    Issue Date
    2008-09-02
    
    Metadata
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    Abstract
    Cancer is the leading cause of disease-related death in teenagers and young adults aged 13-24 years (TYAs) in England. We have analysed national 5-year relative survival among more than 30,000 incident cancer cases in TYAs. For cancer overall, 5-year survival improved from 63% in 1979-84 to 74% during 1996-2001 (P<0.001). However, there were no sustained improvements in survival over time among high-grade brain tumours and bone and soft tissue sarcomas. Survival patterns varied by age group (13-16, 17-20, 21-24 years), sex and diagnosis. Survival from leukaemia and brain tumours was better in the youngest age group but in the oldest from germ-cell tumours (GCTs). For lymphomas, bone and soft tissue sarcomas, melanoma and carcinomas, survival was not significantly associated with age. Females had a better survival than males except for GCTs. Most groups showed no association between survival and socioeconomic deprivation, but for leukaemias, head and neck carcinoma and colorectal carcinoma, survival was significantly poorer with increasing deprivation. These results will aid the development of national specialised service provision for this age group and identify areas of clinical need that present the greatest challenges.
    Citation
    Survival from cancer in teenagers and young adults in England, 1979-2003. 2008, 99 (5):830-5 Br. J. Cancer
    Journal
    British Journal of Cancer
    URI
    http://hdl.handle.net/10541/68837
    DOI
    10.1038/sj.bjc.6604460
    PubMed ID
    18728673
    Type
    Article
    Language
    en
    ISSN
    1532-1827
    ae974a485f413a2113503eed53cd6c53
    10.1038/sj.bjc.6604460
    Scopus Count
    Collections
    All Christie Publications
    North West Cancer Intelligence Service

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