• Login
    View Item 
    •   Home
    • The Manchester Institute Cancer Research UK
    • All Paterson Institute for Cancer Research
    • View Item
    •   Home
    • The Manchester Institute Cancer Research UK
    • All Paterson Institute for Cancer Research
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

    All of ChristieCommunitiesTitleAuthorsIssue DateSubmit DateSubjectsThis CollectionTitleAuthorsIssue DateSubmit DateSubjects

    My Account

    LoginRegister

    Local Links

    The Christie WebsiteChristie Library and Knowledge Service

    Statistics

    Display statistics

    Quantum dots light up pathology.

    • CSV
    • RefMan
    • EndNote
    • BibTex
    • RefWorks
    Authors
    Tholouli, E
    Sweeney, Elizabeth
    Barrow, E
    Clay, V
    Hoyland, Judith A
    Byers, Richard J
    Affiliation
    Department of Clinical Haematology, Manchester Royal Infirmary, Oxford Road, Manchester, UK.
    Issue Date
    2008-11
    
    Metadata
    Show full item record
    Abstract
    Quantum dots (QDs) are novel nanocrystal fluorophores with extremely high fluorescence efficiency and minimal photobleaching. They also possess a constant excitation wavelength together with sharp and symmetrical tunable emission spectra. These unique optical properties make them near-perfect fluorescent markers and there has recently been rapid development of their use for bioimaging. QDs can be conjugated to a wide range of biological targets, including proteins, antibodies, and nucleic acid probes, rendering them of particular interest to pathology researchers. They have been used in multiplex immunohistochemistry and in situ hybridization, which when combined with multispectral imaging, has enabled quantitative measurement of gene expression in situ. QDs have also been used for live in vivo animal imaging and are now being applied to an ever-increasing range of biological problems. These are detailed in this review, which also acts to outline the important advances that have been made in their range of applications. The relative novelty of QDs can present problems in their practical use and guidelines for their application are given.
    Citation
    Quantum dots light up pathology. 2008, 216 (3):275-85 J. Pathol.
    Journal
    The Journal of Pathology
    URI
    http://hdl.handle.net/10541/67995
    DOI
    10.1002/path.2421
    PubMed ID
    18814189
    Type
    Article
    Language
    en
    ISSN
    1096-9896
    ae974a485f413a2113503eed53cd6c53
    10.1002/path.2421
    Scopus Count
    Collections
    All Paterson Institute for Cancer Research
    Clinical and Experimental Pharmacology Group
    School of Cancer and Imaging Sciences

    entitlement

    Related articles

    • Quantum dots brighten biological imaging.
    • Authors: Byers RJ, Hitchman ER
    • Issue date: 2011 Feb
    • Semiconductor quantum dots for biosensing and in vivo imaging.
    • Authors: Xing Y, Xia Z, Rao J
    • Issue date: 2009 Mar
    • From diagnostics to therapy: prospects of quantum dots.
    • Authors: Azzazy HM, Mansour MM, Kazmierczak SC
    • Issue date: 2007 Sep
    • Potentials and pitfalls of fluorescent quantum dots for biological imaging.
    • Authors: Jaiswal JK, Simon SM
    • Issue date: 2004 Sep
    • Biological applications of quantum dots.
    • Authors: Jamieson T, Bakhshi R, Petrova D, Pocock R, Imani M, Seifalian AM
    • Issue date: 2007 Nov
    DSpace software (copyright © 2002 - 2023)  DuraSpace
    Quick Guide | Contact Us
    Open Repository is a service operated by 
    Atmire NV
     

    Export search results

    The export option will allow you to export the current search results of the entered query to a file. Different formats are available for download. To export the items, click on the button corresponding with the preferred download format.

    By default, clicking on the export buttons will result in a download of the allowed maximum amount of items.

    To select a subset of the search results, click "Selective Export" button and make a selection of the items you want to export. The amount of items that can be exported at once is similarly restricted as the full export.

    After making a selection, click one of the export format buttons. The amount of items that will be exported is indicated in the bubble next to export format.