The impact of radiotherapy on swallowing and speech in patients who undergo total laryngectomy.
Affiliation
University Department of Otolaryngology-Head and Neck Surgery, Manchester Royal Infirmary, Manchester, UK. cdecasso@doctors.org.ukIssue Date
2008-12
Metadata
Show full item recordAbstract
OBJECTIVES: Quality of life studies have shown no detrimental effect with radiotherapy (RT) in patients who have a total laryngectomy. We wished to determine the effect of RT (initial or postoperative) specifically on the swallowing and voice function in patients treated by total laryngectomy (TL) for carcinoma of the larynx. DESIGN: Multicenter chart review. SETTING: Multicenter study in the Greater Manchester and Lancashire area. PARTICIPANTS: A total of 121 postlaryngectomy patients all of whom had completed definitive treatment at least 6 months before this study. Twenty-six patients had total laryngectomy as a single modality treatment and 95 had total laryngectomy and radiotherapy. MAIN OUTCOME MEASURES: Swallowing (solid food, soft diet or fluid/PEG) and voice development. RESULTS: Swallowing was better in the group who had no radiotherapy (P = 0.0037). There was no difference in voice function between the two groups. We also demonstrated that females had a worse swallowing outcome (P = 0.0101), as did advanced nodal stage (P = 0.001). CONCLUSIONS: RT adversely affects the swallowing results but not the speech results after TL when given either as initial treatment or postoperatively. This should be kept in mind in the decision-making process in the treatment of patients with carcinoma of the larynx.Citation
The impact of radiotherapy on swallowing and speech in patients who undergo total laryngectomy. 2008, 139 (6):792- 797 Otolaryngol Head Neck SurgJournal
Otolaryngology--Head and Neck SurgeryDOI
10.1016/j.otohns.2008.08.023PubMed ID
19041505Type
ArticleLanguage
enISSN
0194-5998ae974a485f413a2113503eed53cd6c53
10.1016/j.otohns.2008.08.023
Scopus Count
Related articles
- Voice and swallowing outcomes of an organ-preservation trial for advanced laryngeal cancer.
- Authors: Fung K, Lyden TH, Lee J, Urba SG, Worden F, Eisbruch A, Tsien C, Bradford CR, Chepeha DB, Hogikyan ND, Prince ME, Teknos TN, Wolf GT
- Issue date: 2005 Dec 1
- Comparison of quality of life outcomes in laryngeal cancer patients following chemoradiation vs. total laryngectomy.
- Authors: LoTempio MM, Wang KH, Sadeghi A, Delacure MD, Juillard GF, Wang MB
- Issue date: 2005 Jun
- Functional outcomes following treatment for advanced laryngeal cancer. Part I--Voice preservation in advanced laryngeal cancer. Part II--Laryngectomy rehabilitation: the state of the art in the VA System. Research Speech-Language Pathologists. Department of Veterans Affairs Laryngeal Cancer Study Group.
- Authors: Hillman RE, Walsh MJ, Wolf GT, Fisher SG, Hong WK
- Issue date: 1998 May
- Voice and swallowing disorders: functional results and quality of life following supracricoid laryngectomy with cricohyoidoepiglottopexy.
- Authors: Portas JG, Queija Ddos S, Arine LP, Ferreira AS, Dedivitis RA, Lehn CN, Barros AP
- Issue date: 2009 Oct
- Functional outcomes after supracricoid laryngectomy.
- Authors: Zacharek MA, Pasha R, Meleca RJ, Dworkin JP, Stachler RJ, Jacobs JR, Marks SC, Garfield I
- Issue date: 2001 Sep