Changes in cancer incidence in teenagers and young adults (ages 13 to 24 years) in England 1979-2003.
AffiliationCancer Research UK Pediatric and Familial Cancer Research Group, Royal Manchester Children's Hospital, University of Manchester, Stancliffe, Manchester, United Kingdom. firstname.lastname@example.org
MetadataShow full item record
AbstractBACKGROUND: Cancer for teenagers and young adults represents a major source of morbidity and mortality. Trends in cancer incidence can provide pointers concerning how changes in the environment and in personal behavior affect cancer risks. METHODS: Data on 39,129 neoplasms in individuals ages 13 to 24 years who were diagnosed in England from 1979 to 2003 were analyzed. Variability in incidence by time period and differences in the time trends by age group, sex, and geographic region were analyzed using generalized linear models. RESULTS: Incidence rates of leukemias, lymphomas, central nervous system, bone, and germ cell tumors; melanoma; and carcinomas of the thyroid, ovary, cervix, and colon/rectum increased over time (all P < .01); whereas the incidence of carcinomas of the stomach and bladder decreased (both P < .01). These changes were consistent by age, sex, and region for most neoplasms. Melanoma incidence stabilized in southern England by 1993 but continued to increase in northern England (P = .001). The increase in non-Hodgkin lymphoma was greater in individuals ages 20 to 24 year than in younger individuals, but the increase in Hodgkin lymphoma was confined to individuals ages 13 to 14 years. CONCLUSIONS: The changes in incidence rates may have been caused in part by environmental changes and in part by behavioral changes in young individuals. Some of these results can be used to inform public health campaigns, which can be constructed to encourage better lifestyle choices by young individuals.
CitationChanges in cancer incidence in teenagers and young adults (ages 13 to 24 years) in England 1979-2003. 2008, 113 (10):2807-15 Cancer
- Trends in the incidence and survival of cancer in teenagers and young adults: regional analysis for South East England 1960-2002.
- Authors: Croucher C, Whelan JS, Møller H, Davies EA
- Issue date: 2009 Jun
- Incidence and survival for cancer in children and young adults in the North of England, 1968-1995: a report from the Northern Region Young Persons' Malignant Disease Registry.
- Authors: Cotterill SJ, Parker L, Malcolm AJ, Reid M, More L, Craft AW
- Issue date: 2000 Aug
- Cancer in adolescents and young adults aged 15-24 years: a report from the North of England young person's malignant disease registry, UK.
- Authors: Pearce MS, Parker L, Windebank KP, Cotterill SJ, Craft AW
- Issue date: 2005 Oct 15
- Rates of inclusion of teenagers and young adults in England into National Cancer Research Network clinical trials: report from the National Cancer Research Institute (NCRI) Teenage and Young Adult Clinical Studies Development Group.
- Authors: Fern L, Davies S, Eden T, Feltbower R, Grant R, Hawkins M, Lewis I, Loucaides E, Rowntree C, Stenning S, Whelan J, National Cancer Research Institute (NCRI) Teenage and Young Adult Clinical Studies Development Group.
- Issue date: 2008 Dec 16
- Sex-specific incidence and temporal trends in solid tumours in young people from Northern England, 1968-2005.
- Authors: Magnanti BL, Dorak MT, Parker L, Craft AW, James PW, McNally RJ
- Issue date: 2008 Apr 3