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    Adult brain tumour research in 2024: status, challenges and recommendations

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    Authors
    Purshouse, K.
    Bulbeck, H. J.
    Rooney, A. G.
    Noble, K. E.
    Carruthers, R. D.
    Thompson, G.
    Hamerlik, Petra
    Yap, C.
    Kurian, K. M.
    Jefferies, S. J.
    Lopez, J. S.
    Jenkinson, M. D.
    Hanemann, C. O.
    Stead, L. F.
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    Affiliation
    Division of Cancer Sciences, University of Manchester, Manchester, UK.
    Issue Date
    2024
    
    Metadata
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    Abstract
    In 2015, a groundswell of brain tumour patient, carer and charity activism compelled the UK Minister for Life Sciences to form a brain tumour research task and finish group. This resulted, in 2018, with the UK government pledging £20m of funding, to be paralleled with £25m from Cancer Research UK, specifically for neuro-oncology research over the subsequent 5 years. Herein, we review if and how the adult brain tumour research landscape in the United Kingdom has changed over that time and what challenges and bottlenecks remain. We have identified seven universal brain tumour research priorities and three cross-cutting themes, which span the research spectrum from bench to bedside and back again. We discuss the status, challenges and recommendations for each one, specific to the United Kingdom.
    Citation
    Purshouse K, Bulbeck HJ, Rooney AG, Noble KE, Carruthers RD, Thompson G, et al. Adult brain tumour research in 2024: Status, challenges and recommendations. Neuropathology and applied neurobiology. 2024 Apr;50(2):e12979. PubMed PMID: 38605644. Epub 2024/04/12. eng.
    Journal
    Neuropathology and Applied Neurobiology
    URI
    http://hdl.handle.net/10541/627060
    DOI
    10.1111/nan.12979
    PubMed ID
    38605644
    Additional Links
    https://dx.doi.org/10.1111/nan.12979
    Type
    Article
    Language
    en
    ae974a485f413a2113503eed53cd6c53
    10.1111/nan.12979
    Scopus Count
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