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    Streamlining mouse genome editing by integrating AAV repair template delivery and CRISPR-Cas electroporation

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    Authors
    Moncaut, Natalia
    Affiliation
    Genome Editing and Mouse Models, Cancer Research UK Manchester Institute, The University of Manchester, Manchester, UK.
    Issue Date
    2024
    
    Metadata
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    Abstract
    Recent genome editing techniques have substantially simplified the generation of genetically modified mice. A new study combines adeno-associated viruses (AAV) and electroporation to generate a robust pipeline to deliver CRISPR-Cas reagents into mouse embryos.
    Citation
    Moncaut N. Streamlining mouse genome editing by integrating AAV repair template delivery and CRISPR-Cas electroporation. Lab animal. 2024 May;53(5):115-6. PubMed PMID: 38600182. Pubmed Central PMCID: PMC11068566. Epub 2024/04/11. eng.
    Journal
    Lab Animal (NY)
    URI
    http://hdl.handle.net/10541/627046
    DOI
    10.1038/s41684-024-01363-w
    PubMed ID
    38600182
    Additional Links
    https://dx.doi.org/10.1038/s41684-024-01363-w
    Type
    Other
    Language
    en
    ae974a485f413a2113503eed53cd6c53
    10.1038/s41684-024-01363-w
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