Streamlining mouse genome editing by integrating AAV repair template delivery and CRISPR-Cas electroporation
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Authors
Moncaut, NataliaAffiliation
Genome Editing and Mouse Models, Cancer Research UK Manchester Institute, The University of Manchester, Manchester, UK.Issue Date
2024
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Recent genome editing techniques have substantially simplified the generation of genetically modified mice. A new study combines adeno-associated viruses (AAV) and electroporation to generate a robust pipeline to deliver CRISPR-Cas reagents into mouse embryos.Citation
Moncaut N. Streamlining mouse genome editing by integrating AAV repair template delivery and CRISPR-Cas electroporation. Lab animal. 2024 May;53(5):115-6. PubMed PMID: 38600182. Pubmed Central PMCID: PMC11068566. Epub 2024/04/11. eng.Journal
Lab Animal (NY)DOI
10.1038/s41684-024-01363-wPubMed ID
38600182Additional Links
https://dx.doi.org/10.1038/s41684-024-01363-wType
OtherLanguage
enae974a485f413a2113503eed53cd6c53
10.1038/s41684-024-01363-w
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