Treatment response biomarkers: working toward personalized radiotherapy for lung cancer
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Authors
Horne, AshleyHarada, K.
Brown, Katherine D
Chua, K. L. M.
McDonald, F.
Price, Gareth
Putora, P. M.
Rothwell, Dominic G
Faivre-Finn, Corinne
Affiliation
Division of Cancer Sciences, University of Manchester, Manchester, United Kingdom; Department of Radiation Oncology, The Christie NHS Foundation Trust, Manchester, United Kingdom; Department of Research and Innovation, The Christie Hospital NHS Foundation Trust, Manchester, United Kingdom. CR-UK National Biomarker Centre, University of Manchester, Manchester, United Kingdom.Issue Date
2024
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Owing to major advances in the field of radiation oncology, patients with lung cancer can now receive technically individualized radiotherapy treatments. Nevertheless, in the era of precision oncology, radiotherapy-based treatment selection needs to be improved as many patients do not benefit or are not offered optimum therapies. Cost-effective robust biomarkers can address this knowledge gap and lead to individuals being offered more bespoke treatments leading to improved outcome. This narrative review discusses some of the current achievements and challenges in the realization of personalized radiotherapy delivery in patients with lung cancer.Citation
Horne A, Harada K, Brown KD, Chua KLM, McDonald F, Price G, et al. Treatment Response Biomarkers: Working Toward Personalized Radiotherapy for Lung Cancer. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 2024 Apr 12. PubMed PMID: 38615939. Epub 2024/04/15. eng.Journal
Journal of Thoracic OncologyDOI
10.1016/j.jtho.2024.04.006PubMed ID
38615939Additional Links
https://dx.doi.org/10.1016/j.jtho.2024.04.006Type
ArticleLanguage
enae974a485f413a2113503eed53cd6c53
10.1016/j.jtho.2024.04.006
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