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    Treatment response biomarkers: working toward personalized radiotherapy for lung cancer

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    PIIS1556086424001643.pdf
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    Authors
    Horne, Ashley
    Harada, K.
    Brown, Katherine D
    Chua, K. L. M.
    McDonald, F.
    Price, Gareth
    Putora, P. M.
    Rothwell, Dominic G
    Faivre-Finn, Corinne
    Affiliation
    Division of Cancer Sciences, University of Manchester, Manchester, United Kingdom; Department of Radiation Oncology, The Christie NHS Foundation Trust, Manchester, United Kingdom; Department of Research and Innovation, The Christie Hospital NHS Foundation Trust, Manchester, United Kingdom. CR-UK National Biomarker Centre, University of Manchester, Manchester, United Kingdom.
    Issue Date
    2024
    
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    Abstract
    Owing to major advances in the field of radiation oncology, patients with lung cancer can now receive technically individualized radiotherapy treatments. Nevertheless, in the era of precision oncology, radiotherapy-based treatment selection needs to be improved as many patients do not benefit or are not offered optimum therapies. Cost-effective robust biomarkers can address this knowledge gap and lead to individuals being offered more bespoke treatments leading to improved outcome. This narrative review discusses some of the current achievements and challenges in the realization of personalized radiotherapy delivery in patients with lung cancer.
    Citation
    Horne A, Harada K, Brown KD, Chua KLM, McDonald F, Price G, et al. Treatment Response Biomarkers: Working Toward Personalized Radiotherapy for Lung Cancer. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 2024 Apr 12. PubMed PMID: 38615939. Epub 2024/04/15. eng.
    Journal
    Journal of Thoracic Oncology
    URI
    http://hdl.handle.net/10541/627028
    DOI
    10.1016/j.jtho.2024.04.006
    PubMed ID
    38615939
    Additional Links
    https://dx.doi.org/10.1016/j.jtho.2024.04.006
    Type
    Article
    Language
    en
    ae974a485f413a2113503eed53cd6c53
    10.1016/j.jtho.2024.04.006
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