Local control following stereotactic body radiation therapy for liver oligometastases: lessons from a quarter century
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Authors
Mheid, SAllen, S
Ng, SSW
Hall, WA
Sanford, NN
Aguilera, TA
Elamir, AM
Bahij, R
Intven, MPW
Radhakrishna, Ganesh
Mohamad, I
De Leon, J
Tan, H
Lewis, S
Gani, C
Stanecu, T
Dell'Acqua, V
Hosni, A
Affiliation
Department of Radiotherapy, The Christie NHS Foundation Trust, Manchester M20 4BX, UK.Issue Date
2023
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The utilization of stereotactic body radiation therapy for the treatment of liver metastasis has been widely studied and has demonstrated favorable local control outcomes. However, several predictive factors play a crucial role in the efficacy of stereotactic body radiation therapy, such as the number and size (volume) of metastatic liver lesions, the primary tumor site (histology), molecular biomarkers (e.g., KRAS and TP53 mutation), the use of systemic therapy prior to SBRT, the radiation dose, and the use of advanced technology and organ motion management during SBRT. These prognostic factors need to be considered when clinical trials are designed to evaluate the efficacy of SBRT for liver metastases.Citation
Mheid S, Allen S, Ng SSW, Hall WA, Sanford NN, Aguilera TA, et al. Local Control Following Stereotactic Body Radiation Therapy for Liver Oligometastases: Lessons from a Quarter Century. CURRENT ONCOLOGY. 2023 OCT;30(10):9230-43. PubMed PMID: WOS:001094095600001. English.Journal
Current OncologyDOI
10.3390/curroncol30100667PubMed ID
37887567Additional Links
https://dx.doi.org/10.3390/curroncol30100667Type
ArticleLanguage
enae974a485f413a2113503eed53cd6c53
10.3390/curroncol30100667
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