How to compose platform trials
| dc.contributor.author | Clarke, Noel W | en |
| dc.contributor.author | James, ND | en |
| dc.date.accessioned | 2023-12-28T16:04:43Z | |
| dc.date.available | 2023-12-28T16:04:43Z | |
| dc.date.issued | 2023 | en |
| dc.identifier.citation | Clarke NW, James ND. How to Compose Platform Trials. Eur Urol Focus. 2023 Nov 2. PubMed PMID: 37925327. Epub 2023/11/05. eng. | en |
| dc.identifier.pmid | 37925327 | en |
| dc.identifier.doi | 10.1016/j.euf.2023.10.016 | en |
| dc.identifier.uri | http://hdl.handle.net/10541/626721 | |
| dc.description.abstract | Platform trials are adaptive randomised controlled trials that address multiple questions using a single protocol, which reduces the time taken to reach a meaningful trial endpoint. This mini review provides a description of how to conceive, design, and carry out a platform trial in urology, using experience gained in the STAMPEDE trial. PATIENT SUMMARY: Clinical trials to test how well a new drug or treatment works can take a long time before meaningful results can be assessed. Trials with a platform design can test multiple treatments using just one protocol and control, which reduces the time taken to reach a trial endpoint. | en |
| dc.language.iso | en | en |
| dc.relation.url | https://dx.doi.org/10.1016/j.euf.2023.10.016 | en |
| dc.title | How to compose platform trials | en |
| dc.type | Article | en |
| dc.contributor.department | Department of Urology, The Christie Hospital, Manchester, UK. | en |
| dc.identifier.journal | European Urology Focus | en |
| dc.description.note | en] |