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    Adaptive radiotherapy for breast cancer

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    PIIS2405630822001227.pdf
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    Journal article
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    Authors
    De-Colle, C.
    Kirby, A.
    Russell, N.
    Shaitelman, S. F.
    Currey, A.
    Donovan, E.
    Hahn, E.
    Han, K.
    Anandadas, Carmel N
    Mahmood, F.
    Lorenzen, E. L.
    van den Bongard, D.
    Groot Koerkamp, M. L.
    Houweling, A. C.
    Nachbar, M.
    Thorwarth, D.
    Zips, D.
    Show allShow less
    Affiliation
    Department of Radiation Oncology, University Hospital and Medical Faculty, Eberhard Karls University Tübingen, Tübingen, Germany
    Issue Date
    2023
    
    Metadata
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    Abstract
    Research in the field of local and locoregional breast cancer radiotherapy aims to maintain excellent oncological outcomes while reducing treatment-related toxicity. Adaptive radiotherapy (ART) considers variations in target and organs at risk (OARs) anatomy occurring during the treatment course and integrates these in re-optimized treatment plans. Exploiting ART routinely in clinic may result in smaller target volumes and better OAR sparing, which may lead to reduction of acute as well as late toxicities. In this review MR-guided and CT-guided ART for breast cancer patients according to different clinical scenarios (neoadjuvant and adjuvant partial breast irradiation, whole breast, chest wall and regional nodal irradiation) are reviewed and their advantages as well as challenging aspects discussed.
    Citation
    De-Colle C, Kirby A, Russell N, Shaitelman SF, Currey A, Donovan E, et al. Adaptive radiotherapy for breast cancer. Clinical and translational radiation oncology. 2023 Mar;39:100564. PubMed PMID: 36632056. Pubmed Central PMCID: PMC9826896. Epub 2023/01/13. eng.
    Journal
    Clinical and Translational Radiation Oncology
    URI
    http://hdl.handle.net/10541/625997
    DOI
    10.1016/j.ctro.2022.100564
    PubMed ID
    36632056
    Additional Links
    https://dx.doi.org/10.1016/j.ctro.2022.100564
    Type
    Article
    Language
    en
    ae974a485f413a2113503eed53cd6c53
    10.1016/j.ctro.2022.100564
    Scopus Count
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