Authors
Jørgensen, ClausAffiliation
Systems Oncology, Cancer Research UK Manchester Institute, University of Manchester, Alderley Park, Manchester, SK10 4TG, UK.Issue Date
2022
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Show full item recordAbstract
Pancreatic ductal adenocarcinoma is characterized by a complex microenvironment. In this issue of Cancer Cell, Chen and colleagues define an oncogenic role of tumor-cell-produced collagen I homotrimers, wherein tumor development is promoted by integrin α3/β1-dependent activation of tumor cell signaling and modulation of tumor microbiome and immunity.Citation
Jørgensen C. Untangling the tumorigenic role of homotrimeric collagen I. Cancer cell. 2022 Aug 8;40(8):802-4. PubMed PMID: 35944498. Epub 2022/08/10. eng.Journal
Cancer CellDOI
10.1016/j.ccell.2022.07.007PubMed ID
35944498Additional Links
https://dx.doi.org/10.1016/j.ccell.2022.07.007Type
OtherLanguage
enae974a485f413a2113503eed53cd6c53
10.1016/j.ccell.2022.07.007
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