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dc.contributor.authorFernandes, S.
dc.contributor.authorVyas, C.
dc.contributor.authorLim, P.
dc.contributor.authorPereira, R. F.
dc.contributor.authorVirós, Amaya
dc.contributor.authorBártolo, P.
dc.date.accessioned2022-08-31T11:38:30Z
dc.date.available2022-08-31T11:38:30Z
dc.date.issued2022en
dc.identifier.citationFernandes S, Vyas C, Lim P, Pereira RF, Virós A, Bártolo P. 3D Bioprinting: An Enabling Technology to Understand Melanoma. Cancers (Basel). 2022 Jul 20;14(14). PubMed PMID: 35884596. Pubmed Central PMCID: PMC9318274. Epub 2022/07/28. eng.en
dc.identifier.pmid35884596en
dc.identifier.doi10.3390/cancers14143535en
dc.identifier.urihttp://hdl.handle.net/10541/625538
dc.description.abstractMelanoma is a potentially fatal cancer with rising incidence over the last 50 years, associated with enhanced sun exposure and ultraviolet radiation. Its incidence is highest in people of European descent and the ageing population. There are multiple clinical and epidemiological variables affecting melanoma incidence and mortality, such as sex, ethnicity, UV exposure, anatomic site, and age. Although survival has improved in recent years due to advances in targeted and immunotherapies, new understanding of melanoma biology and disease progression is vital to improving clinical outcomes. Efforts to develop three-dimensional human skin equivalent models using biofabrication techniques, such as bioprinting, promise to deliver a better understanding of the complexity of melanoma and associated risk factors. These 3D skin models can be used as a platform for patient specific models and testing therapeutics.en
dc.language.isoenen
dc.relation.urlhttps://dx.doi.org/10.3390/cancers14143535en
dc.title3D Bioprinting: an enabling technology to understand melanomaen
dc.typeArticleen
dc.contributor.departmentDepartment of Mechanical, Aerospace and Civil Engineering, University of Manchester, Oxford Road, Manchester M13 9PL, UKen
dc.identifier.journalCancersen
dc.description.noteen]
refterms.dateFOA2022-08-31T12:11:21Z


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