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Affiliation
Department of Mechanical, Aerospace and Civil Engineering, University of Manchester, Oxford Road, Manchester M13 9PL, UKIssue Date
2022
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Melanoma is a potentially fatal cancer with rising incidence over the last 50 years, associated with enhanced sun exposure and ultraviolet radiation. Its incidence is highest in people of European descent and the ageing population. There are multiple clinical and epidemiological variables affecting melanoma incidence and mortality, such as sex, ethnicity, UV exposure, anatomic site, and age. Although survival has improved in recent years due to advances in targeted and immunotherapies, new understanding of melanoma biology and disease progression is vital to improving clinical outcomes. Efforts to develop three-dimensional human skin equivalent models using biofabrication techniques, such as bioprinting, promise to deliver a better understanding of the complexity of melanoma and associated risk factors. These 3D skin models can be used as a platform for patient specific models and testing therapeutics.Citation
Fernandes S, Vyas C, Lim P, Pereira RF, Virós A, Bártolo P. 3D Bioprinting: An Enabling Technology to Understand Melanoma. Cancers (Basel). 2022 Jul 20;14(14). PubMed PMID: 35884596. Pubmed Central PMCID: PMC9318274. Epub 2022/07/28. eng.Journal
CancersDOI
10.3390/cancers14143535PubMed ID
35884596Additional Links
https://dx.doi.org/10.3390/cancers14143535Type
ArticleLanguage
enae974a485f413a2113503eed53cd6c53
10.3390/cancers14143535