• Login
    View Item 
    •   Home
    • The Manchester Institute Cancer Research UK
    • All Paterson Institute for Cancer Research
    • View Item
    •   Home
    • The Manchester Institute Cancer Research UK
    • All Paterson Institute for Cancer Research
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

    All of ChristieCommunitiesTitleAuthorsIssue DateSubmit DateSubjectsThis CollectionTitleAuthorsIssue DateSubmit DateSubjects

    My Account

    LoginRegister

    Local Links

    The Christie WebsiteChristie Library and Knowledge Service

    Statistics

    Display statistics

    Pathways from diagnosis to death from keratinocyte cancer in kidney transplant recipients

    • CSV
    • RefMan
    • EndNote
    • BibTex
    • RefWorks
    Thumbnail
    Name:
    35439759.pdf
    Size:
    221.8Kb
    Format:
    PDF
    Description:
    Identified with Open Access button
    Download
    Authors
    Shao, E. X.
    Khosrotehrani, K.
    Campbell, S.
    Isbel, N.
    Green, Adèle C
    Affiliation
    QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia
    Issue Date
    2022
    
    Metadata
    Show full item record
    Abstract
    Background: Kidney transplant recipients are at increased risk of developing and dying from keratinocyte cancer. We aimed to describe the clinical course of keratinocyte cancer-related deaths in a cohort of kidney transplant recipients. Methods: In kidney transplant recipients transplanted between 1995 and 2014 in Queensland, Australia, we ascertained keratinocyte cancer deaths by searching national transplant and state death registries to March 2020. Deceased transplant recipients' medical records were reviewed to assess features of the primary lesion of the fatal keratinocyte cancer, metastases, and clinical information before death. Results: Of 658 kidney transplant recipient deaths, 49 (7%) were due to keratinocyte cancer, and medical records were available for 36 (73%). One death was due to basal cell carcinoma, and 35 were from squamous cell carcinoma (SCC), primarily from the head and neck (24; 69%). The most common site of metastasis was the lungs (21; 58%). Median time (minimum, maximum) from the diagnosis of primary SCC to metastasis was 5 months (0, 29). After this, the median time to death was 9 months (1, 50). Conclusion: Fatal keratinocyte cancers overwhelmingly arise on the head and neck, with lungs the most common metastasis site. The short time from diagnosis of primary to death indicates the aggressive nature of these keratinocyte cancers.
    Citation
    Shao EX, Khosrotehrani K, Campbell S, Isbel N, Green A. Pathways from Diagnosis to Death from Keratinocyte Cancer in Kidney Transplant Recipients. Dermatology. S. Karger AG; 2022. p. 1–8.
    Journal
    Dermatology
    URI
    http://hdl.handle.net/10541/625285
    DOI
    10.1159/000524120
    PubMed ID
    35439759
    Additional Links
    https://dx.doi.org/10.1159/000524120
    Type
    Article
    Language
    en
    ae974a485f413a2113503eed53cd6c53
    10.1159/000524120
    Scopus Count
    Collections
    All Paterson Institute for Cancer Research

    entitlement

    Related articles

    • Keratinocyte Cancer Mortality in Kidney Transplant Recipients.
    • Authors: Shao EX, Betz-Stablein B, Khosrotehrani K, Campbell S, Isbel N, Green AC
    • Issue date: 2022 May 1
    • Association between Use of Hydrochlorothiazide and Risk of Keratinocyte Cancers in Kidney Transplant Recipients.
    • Authors: Letellier T, Le Borgne F, Kerleau C, Gaultier A, Dantal J, Ville S, Divat Consortium
    • Issue date: 2020 Dec 7
    • Risk of Second Malignancies in Solid Organ Transplant Recipients Who Develop Keratinocyte Cancers.
    • Authors: Zamoiski RD, Yanik E, Gibson TM, Cahoon EK, Madeleine MM, Lynch CF, Gustafson S, Goodman MT, Skeans M, Israni AK, Engels EA, Morton LM
    • Issue date: 2017 Aug 1
    • Higher mycophenolate dosage is associated with an increased risk of squamous cell carcinoma in kidney transplant recipients.
    • Authors: Shao EX, Betz-Stablein B, Marquat L, Campbell S, Isbel N, Green AC, Plasmeijer EI
    • Issue date: 2022 Dec
    • The presence of betapapillomavirus antibodies around transplantation predicts the development of keratinocyte carcinoma in organ transplant recipients: a cohort study.
    • Authors: Genders RE, Mazlom H, Michel A, Plasmeijer EI, Quint KD, Pawlita M, van der Meijden E, Waterboer T, de Fijter H, Claas FH, Wolterbeek R, Feltkamp MCW, Bouwes Bavinck JN
    • Issue date: 2015 May
    DSpace software (copyright © 2002 - 2023)  DuraSpace
    Quick Guide | Contact Us
    Open Repository is a service operated by 
    Atmire NV
     

    Export search results

    The export option will allow you to export the current search results of the entered query to a file. Different formats are available for download. To export the items, click on the button corresponding with the preferred download format.

    By default, clicking on the export buttons will result in a download of the allowed maximum amount of items.

    To select a subset of the search results, click "Selective Export" button and make a selection of the items you want to export. The amount of items that can be exported at once is similarly restricted as the full export.

    After making a selection, click one of the export format buttons. The amount of items that will be exported is indicated in the bubble next to export format.