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    Evaluation of Prognostic and Predictive Models in the Oncology Clinic

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    Authors
    Craddock, M.
    Crockett, C.
    McWilliam, A.
    Price, G.
    Sperrin, M.
    van der Veer, S. N.
    Faivre-Finn, C.
    Affiliation
    University of Manchester, Radiotherapy Related Research Group, Division of Cancer Sciences, School of Medical Sciences, Manchester, UK
    Issue Date
    2021
    
    Metadata
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    Abstract
    Predictive and prognostic models hold great potential to support clinical decision making in oncology and could ultimately facilitate a paradigm shift to a more personalised form of treatment. While a large number of models relevant to the field of oncology have been developed, few have been translated into clinical use and assessment of clinical utility is not currently considered a routine part of model development. In this narrative review of the clinical evaluation of prediction models in oncology, we propose a high-level process diagram for the life cycle of a clinical model, encompassing model commissioning, clinical implementation and ongoing quality assurance, which aims to bridge the gap between model development and clinical implementation.
    Citation
    Craddock M, Crockett C, McWilliam A, Price G, Sperrin M, van der Veer SN, et al. Evaluation of Prognostic and Predictive Models in the Oncology Clinic. Clin Oncol (R Coll Radiol). 2021.
    Journal
    Clin Oncol (R Coll Radiol)
    URI
    http://hdl.handle.net/10541/625014
    DOI
    10.1016/j.clon.2021.11.022
    PubMed ID
    34922799
    Additional Links
    https://dx.doi.org/10.1016/j.clon.2021.11.022
    Type
    Article
    Language
    en
    ae974a485f413a2113503eed53cd6c53
    10.1016/j.clon.2021.11.022
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