Induction of APOBEC3 exacerbates DNA replication stress and chromosomal instability in early breast and lung cancer evolution
Authors
Venkatesan, S.Angelova, M.
Puttick, C.
Zhai, H. R.
Caswell, D. R.
Lu, W. T.
Dietzen, M.
Galanos, P.
Evangelou, K.
Bellelli, R.
Lim, E. L.
Watkins, T. B. K.
Rowan, A.
Teixeira, V. H.
Zhao, Y.
Chen, H. Q.
Ngo, B.
Zalmas, L. P.
Al Bakir, M.
Hobor, S.
Gronroos, E.
Pennycuick, A.
Nigro, E.
Campbell, B. B.
Brown, W. L.
Akarca, A. U.
Marafioti, T.
Wu, M. Y.
Howell, M.
Boulton, S. J.
Bertoli, C.
Fenton, T. R.
de Bruin, R. A. M.
Maya-Mendoza, A.
Santoni-Rugiu, E.
Hynds, R. E.
Gorgoulis, Vassilis G
Jamal-Hanjani, M.
McGranahan, N.
Harris, R. S.
Janes, S. M.
Bartkova, J.
Bakhoum, S. F.
Bartek, J.
Kanu, N.
Swanton, C.
Consortium, T. R.
Affiliation
Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, LondonIssue Date
2021
Metadata
Show full item recordCitation
Venkatesan S, Angelova M, Puttick C, Zhai H, Caswell DR, Lu W-T, et al. Induction of APOBEC3 Exacerbates DNA Replication Stress and Chromosomal Instability in Early Breast and Lung Cancer Evolution Vol. 11, Cancer Discovery. American Association for Cancer Research (AACR); 2021. p. 2456–73.Journal
Cancer DiscoveryDOI
10.1158/2159-8290.Cd-20-0725PubMed ID
33947663Type
Articleae974a485f413a2113503eed53cd6c53
10.1158/2159-8290.Cd-20-0725
Scopus Count
Collections
Related articles
- DNA replication stress mediates APOBEC3 family mutagenesis in breast cancer.
- Authors: Kanu N, Cerone MA, Goh G, Zalmas LP, Bartkova J, Dietzen M, McGranahan N, Rogers R, Law EK, Gromova I, Kschischo M, Walton MI, Rossanese OW, Bartek J, Harris RS, Venkatesan S, Swanton C
- Issue date: 2016 Sep 15
- Mechanisms of APOBEC3 mutagenesis in human cancer cells.
- Authors: Petljak M, Dananberg A, Chu K, Bergstrom EN, Striepen J, von Morgen P, Chen Y, Shah H, Sale JE, Alexandrov LB, Stratton MR, Maciejowski J
- Issue date: 2022 Jul
- Replication timing alterations are associated with mutation acquisition during breast and lung cancer evolution.
- Authors: Dietzen M, Zhai H, Lucas O, Pich O, Barrington C, Lu WT, Ward S, Guo Y, Hynds RE, Zaccaria S, Swanton C, McGranahan N, Kanu N
- Issue date: 2024 Jul 18
- Clinical Implications of APOBEC3-Mediated Mutagenesis in Breast Cancer.
- Authors: Roelofs PA, Martens JWM, Harris RS, Span PN
- Issue date: 2023 May 1
- APOBEC3B and APOBEC mutational signature as potential predictive markers for immunotherapy response in non-small cell lung cancer.
- Authors: Wang S, Jia M, He Z, Liu XS
- Issue date: 2018 Jul