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dc.contributor.authorPapaspyropoulos, A.
dc.contributor.authorHazapis, O.
dc.contributor.authorLagopati, N.
dc.contributor.authorPolyzou, A.
dc.contributor.authorPapanastasiou, A. D.
dc.contributor.authorLiontos, M.
dc.contributor.authorGorgoulis, Vassilis G
dc.contributor.authorKotsinas, A.
dc.date.accessioned2021-11-26T10:04:46Z
dc.date.available2021-11-26T10:04:46Z
dc.date.issued2021en
dc.identifier.citationPapaspyropoulos A, Hazapis O, Lagopati N, Polyzou A, Papanastasiou AD, Liontos M, et al. The Role of Circular RNAs in DNA Damage Response and Repair [Internet]. Vol. 13, Cancers. MDPI AG; 2021. p. 5352.en
dc.identifier.pmid34771517en
dc.identifier.doi10.3390/cancers13215352en
dc.identifier.urihttp://hdl.handle.net/10541/624801
dc.description.abstractCircular RNAs (circRNA) comprise a distinct class of non-coding RNAs that are abundantly expressed in the cell. CircRNAs have the capacity to regulate gene expression by interacting with regulatory proteins and/or other classes of RNAs. While a vast number of circRNAs have been discovered, the majority still remains poorly characterized. Particularly, there is no detailed information on the identity and functional role of circRNAs that are transcribed from genes encoding components of the DNA damage response and repair (DDRR) network. In this article, we not only review the available published information on DDRR-related circRNAs, but also conduct a bioinformatic analysis on data obtained from public repositories to uncover deposited, yet uncharacterized circRNAs derived from components of the DDRR network. Finally, we interrogate for potential targets that are regulated by this class of molecules and look into potential functional implications.en
dc.language.isoenen
dc.relation.urlhttps://dx.doi.org/10.3390/cancers13215352en
dc.titleThe role of circular RNAs in DNA damage response and repairen
dc.typeArticleen
dc.contributor.departmentMolecular Carcinogenesis Group, Department of Histology and Embryology, Medical School, National Kapodistrian University of Athens (NKUA), 75 Mikras Asias Str., Goudi, GR-11527 Athens, Greeceen
dc.identifier.journalCancersen
dc.description.noteen]
refterms.dateFOA2021-12-01T10:37:21Z


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