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    Positive attributes of anti-TERT CD4 T-Helper Type 1 immune responses in melanoma

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    Authors
    Nagore, E.
    Virós, Amaya
    Kumar, R.
    Affiliation
    Department of Dermatology, Instituto Valenciano de Oncologia, Valencia, Spain
    Issue Date
    2021
    
    Metadata
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    Abstract
    Nardin et al's (2021) study on melanoma reports anti-TERT CD4 T helper type (Th) 1 responses in more than half of patients. Besides indicating a trend for improved survival, increased anti-TERT CD4 Th1 responses predicted better outcomes for patients treated with immune checkpoint inhibitors. Thus, harnessing systemic anti-TERT CD4 Th1 responses together with tumor-specific elevation of telomerase can potentially open new avenues for biomarkers and treatment in melanoma.
    Citation
    Nagore E, Virós A, Kumar R. Positive Attributes of Anti-TERT CD4 T-Helper Type 1 Immune Responses in Melanoma [Internet]. Journal of Investigative Dermatology. Elsevier BV; 2021.
    Journal
    Journal of Investigative Dermatology
    URI
    http://hdl.handle.net/10541/624796
    DOI
    10.1016/j.jid.2021.09.005
    PubMed ID
    34666894
    Additional Links
    https://dx.doi.org/10.1016/j.jid.2021.09.005
    Type
    Other
    Language
    en
    ae974a485f413a2113503eed53cd6c53
    10.1016/j.jid.2021.09.005
    Scopus Count
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    All Paterson Institute for Cancer Research

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