Show simple item record

dc.contributor.authorKamposioras, Konstantinos
dc.contributor.authorGeraghty, J.
dc.contributor.authorAppleyard, J.
dc.contributor.authorDawod, M.
dc.contributor.authorPapadimitriou, K.
dc.contributor.authorLamarca, Angela
dc.contributor.authorAnthoney, A.
dc.date.accessioned2021-10-28T09:26:07Z
dc.date.available2021-10-28T09:26:07Z
dc.date.issued2021en
dc.identifier.citationKamposioras K, Geraghty J, Appleyard J, Dawod M, Papadimitriou K, Lamarca A, et al. Pancreaticobiliary Malignancies in the Emergency Room: Management of Acute Complications and Oncological Emergencies. Journal of Gastrointestinal Cancer. Springer Science and Business Media LLC; 2021.en
dc.identifier.pmid34648136en
dc.identifier.doi10.1007/s12029-021-00718-7en
dc.identifier.urihttp://hdl.handle.net/10541/624685
dc.description.abstractBackground: Management of pancreaticobiliary (PB) malignancies remains a clinical challenge. In this review, we focus on the management of oncological emergencies in PB malignancies and the potential complication of associated therapeutic interventions. Methods: Biobliographic review of current evidence on the management of oncological emergencies, their potential complications, as well as synthesis of recommendations was performed. The pathogenesis, frequency, related symptoms as well as appropriate investigations are presented. Results: The oncologic emergencies in PB patients were summarised in six categories: (1) hematological (including febrile neutropaenia, thrombocytopenia, coagulopathies), (2) gastrointestinal (gastric outlet and biliary obstruction, gastrointestinal bleeding), (3) thromboembolic events, (4) ascites, (5) metabolic disorders and (6) neurologic complications. The pathogenesis, frequency, related symptoms as well as appropriate investigations are also presented. Conclusion: Patients with PB malignancies are at increased risk of a wide variation of medical emergencies. Clinical knowledge, early recognition and collaboration with the relevant specialties are critical to manage these complications effectively, tailoring overall management around the actual prognosis and individuals' expectations.en
dc.language.isoenen
dc.relation.urlhttps://dx.doi.org/10.1007/s12029-021-00718-7en
dc.titlePancreaticobiliary malignancies in the emergency room: management of acute complications and oncological emergenciesen
dc.typeArticleen
dc.contributor.departmentThe Christie NHS Foundation Trust, Manchester, Greater Manchester, UKen
dc.identifier.journalJournal of Gastrointestinal Canceren
dc.description.noteen]
refterms.dateFOA2021-11-03T09:02:39Z


Files in this item

Thumbnail
Name:
34648136.pdf
Size:
938.5Kb
Format:
PDF
Description:
From UNPAYWALL

This item appears in the following Collection(s)

Show simple item record