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dc.contributor.authorFinch, A. J.
dc.contributor.authorBaena, Esther
dc.date.accessioned2021-09-30T11:56:12Z
dc.date.available2021-09-30T11:56:12Z
dc.date.issued2021en
dc.identifier.citationFinch AJ, Baena E. Spatiofunctional Dynamics of NKX3.1 to Safeguard the Prostate from Cancer. Cancer Discov. 2021 Sep;11(9):2132–4.en
dc.identifier.pmid34479975en
dc.identifier.doi10.1158/2159-8290.Cd-21-0861en
dc.identifier.urihttp://hdl.handle.net/10541/624638
dc.description.abstractA novel role of NKX3.1 in the mitochondria regulating the transcription of the electron transport chain components is reported. Mechanistically, HSPA9 chaperones NKX3.1 into the mitochondria in response to oxidative stress to regulate reactive oxygen species and suppress tumor initiation.See related article by Papachristodoulou et al., p. 2316.en
dc.language.isoenen
dc.relation.urlhttps://dx.doi.org/10.1158/2159-8290.Cd-21-0861en
dc.titleSpatiofunctional dynamics of NKX3.1 to safeguard the prostate from canceren
dc.typeArticleen
dc.contributor.departmentCentre for Tumour Biology, Barts Cancer Institute, Queen Mary University of London, London, United Kingdomen
dc.identifier.journalCancer Discoveryen
dc.description.noteen]
refterms.dateFOA2021-10-13T07:51:47Z


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