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dc.contributor.authorNossiter, J.
dc.contributor.authorMorris, M.
dc.contributor.authorCowling, T. E.
dc.contributor.authorParry, M. G.
dc.contributor.authorSujenthiran, A.
dc.contributor.authorAggarwal, A.
dc.contributor.authorPayne, H.
dc.contributor.authorvan der Meulen, J.
dc.contributor.authorClarke, Noel W
dc.contributor.authorCathcart, P.
dc.date.accessioned2021-09-30T11:56:02Z
dc.date.available2021-09-30T11:56:02Z
dc.date.issued2021en
dc.identifier.citationNossiter J, Morris M, Cowling TE, Parry MG, Sujenthiran A, Aggarwal A, et al. Hospital volume and outcomes after radical prostatectomy: a national population-based study using patient-reported urinary continence and sexual function. Prostate Cancer Prostatic Dis. 2021 Sep 8.en
dc.identifier.pmid34493839en
dc.identifier.doi10.1038/s41391-021-00443-zen
dc.identifier.urihttp://hdl.handle.net/10541/624600
dc.description.abstractBackground: Improvements in short-term outcomes have been reported for hospitals with higher radical prostatectomy (RP) volumes. However, the association with longer-term functional outcomes is unknown. Methods: All patients diagnosed with non-metastatic prostate cancer in the English NHS between 2014 and 2016 who underwent RP (N = 10,089) were mailed a survey ≥18 months after diagnosis. Differences in patient-reported urinary continence and sexual function (EPIC-26 on scale from 0 to 100) by hospital volume group (≤60, 61-100, 101-140, >140 RPs/year) were estimated using multilevel linear regression. Results: Overall, 7702 men (76.3%) responded. There were no statistically significant differences in urinary continence (p = 0.08) or sexual function scores with increasing volume group (p = 0.2). When modelled as a linear function, we found a non-significant increase of 0.70 (95% CI -0.41 to 1.80; p = 0.22) in urinary continence and a significant increase of 1.54 (0.62-2.45; p = 0.001) in sexual function scores for a 100-procedure increase in hospital volume, which did not meet the threshold for a minimal clinically important difference (10-12 points). The results were similar for robotic-assisted RP (5529 men [71.8%]). Conclusions: These results do not support further centralisation of RP services beyond levels in England where four in five hospitals perform >60 RPs/year.en
dc.language.isoenen
dc.relation.urlhttps://dx.doi.org/10.1038/s41391-021-00443-zen
dc.titleHospital volume and outcomes after radical prostatectomy: a national population-based study using patient-reported urinary continence and sexual functionen
dc.typeArticleen
dc.contributor.departmentDepartment of Health Services Research and Policy, London School of Hygiene and Tropical Medicine, London, UK.en
dc.identifier.journalProstate Cancer and Prostatic Diseasesen
dc.description.noteen]


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